The Effects of the Endocrine System on Endometrial Cancer

NCT ID: NCT01075386

Last Updated: 2019-08-28

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

75 participants

Study Classification

OBSERVATIONAL

Study Start Date

2009-10-31

Study Completion Date

2018-12-31

Brief Summary

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Endometrial cancer usually begins in the endometrium, which is the tissue lining of the uterus. Endometrial cancer is the most commonly diagnosed gynaecological malignancy in Australia. It affects 1 in 80 Australian women and there are about 1400 new cases and 260 deaths from the disease every year. Most affected women are aged between 50 and 70 years. The purpose of this study is to investigate the possible role of the endocrine system in the regulation of human endometrial cancer. By looking at the laboratory results of people with endometrial cancer and also those without endometrial cancer we hope to gain a better understanding of how endometrial cancer develops and progresses. This may lead to the development of new, effective therapies for endometrial cancer.

Detailed Description

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Conditions

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Endometrial Cancer

Study Design

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Observational Model Type

CASE_CONTROL

Study Time Perspective

PROSPECTIVE

Study Groups

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Grade 2

Patients with Endometrial cancer of Grade 1 differentiation

No interventions assigned to this group

Benign

Patients without endometrial cancer

No interventions assigned to this group

Grade 1

Patients with Endometrial cancer of Grade 2 differentiation

No interventions assigned to this group

Grade 3

Patients with Endometrial cancer of Grade 3 differentiation

No interventions assigned to this group

Eligibility Criteria

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Inclusion Criteria

* women aged 18 years or older
* having a hysterectomy for the treatment of endometrial cancer, fibroids, chronic pelvic pain or abnormal uterine bleeding
* have provided informed consent
Minimum Eligible Age

18 Years

Eligible Sex

FEMALE

Accepts Healthy Volunteers

No

Sponsors

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Greenslopes Private Hospital

UNKNOWN

Sponsor Role collaborator

The University of Queensland

OTHER

Sponsor Role collaborator

Sullivan Nicolaides Pathology

INDUSTRY

Sponsor Role collaborator

Queensland Centre for Gynaecological Cancer

OTHER_GOV

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Chen Chen, MD PhD

Role: STUDY_CHAIR

The University of Queensland

Locations

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Greenslopes Private Hospital

Greenslopes, Queensland, Australia

Site Status

Countries

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Australia

Other Identifiers

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Endo01

Identifier Type: -

Identifier Source: org_study_id

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