Methylated Biomarkers Predictive of Endometrial Cancer Risk

NCT ID: NCT06800677

Last Updated: 2025-01-30

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

ACTIVE_NOT_RECRUITING

Total Enrollment

200 participants

Study Classification

OBSERVATIONAL

Study Start Date

2024-07-31

Study Completion Date

2026-12-31

Brief Summary

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The goal of this observational study is to identify endometrial cancer risk predictive biomarkers and to optimise the methodology for their detection and quantification in non-invasive samples.

Detailed Description

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Conditions

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Endometrial Cancer

Study Design

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Observational Model Type

CASE_CONTROL

Study Time Perspective

PROSPECTIVE

Study Groups

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Cases

Women diagnosed with endometrial cancer of any grade, stage and histological type

Hysterectomy

Intervention Type PROCEDURE

Elective hysterectomy

Controls

Women undergoing a hysterectomy for benign indications

Hysterectomy

Intervention Type PROCEDURE

Elective hysterectomy

Interventions

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Hysterectomy

Elective hysterectomy

Intervention Type PROCEDURE

Eligibility Criteria

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Inclusion Criteria

1. Women aged 45-70 years
2. Attending St Mary's Hospital, Manchester for an elective hysterectomy by any route for either the treatment of endometrial cancer or a benign gynaecological condition
3. Able to consent to participation in the study

Exclusion Criteria

1. Presence of malignancy asides from endometrial cancer
2. Undergoing elective hysterectomy for suspected ovarian cancer
Minimum Eligible Age

45 Years

Maximum Eligible Age

70 Years

Eligible Sex

FEMALE

Accepts Healthy Volunteers

No

Sponsors

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Queen Mary University of London

OTHER

Sponsor Role collaborator

University of Manchester

OTHER

Sponsor Role lead

Responsible Party

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Sarah Kitson

Clinical Lecturer

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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Manchester University NHS Foundation Trust

Manchester, , United Kingdom

Site Status

Countries

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United Kingdom

Other Identifiers

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334940

Identifier Type: -

Identifier Source: org_study_id

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