Cerebrovascular Autoregulation During Sepsis

NCT ID: NCT01029080

Last Updated: 2013-04-15

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

30 participants

Study Classification

OBSERVATIONAL

Study Start Date

2009-12-31

Study Completion Date

2011-03-31

Brief Summary

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The aim of the study is to correlate the dynamic cerebrovascular autoregulation by patients with sepsis with a sepsis-associated delirium.

Detailed Description

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Conditions

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Sepsis Delirium

Study Design

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Observational Model Type

CASE_ONLY

Study Time Perspective

PROSPECTIVE

Study Groups

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Sepsis

All patients with sepsis defined by actually sepsis guidelines

no interventions

Intervention Type OTHER

No interventions

Interventions

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no interventions

No interventions

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* clinical symptoms of sepsis, severe sepsis and septic shock
* possibility for measurement of transcranial doppler ultrasound
* age over 18 years

Exclusion Criteria

* preexisting cerebrovascular disease
* preexisting immunological disease
* traumatic brain injury
* intracranial infectious disease
* pregnancy
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Johannes Gutenberg University Mainz

OTHER

Sponsor Role lead

Responsible Party

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Patrick Schramm

Senior Physician

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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University medical centre Mainz

Mainz, , Germany

Site Status

Countries

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Germany

References

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Schramm P, Klein KU, Falkenberg L, Berres M, Closhen D, Werhahn KJ, David M, Werner C, Engelhard K. Impaired cerebrovascular autoregulation in patients with severe sepsis and sepsis-associated delirium. Crit Care. 2012 Oct 4;16(5):R181. doi: 10.1186/cc11665.

Reference Type RESULT
PMID: 23036135 (View on PubMed)

Other Identifiers

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837.435.08

Identifier Type: -

Identifier Source: org_study_id

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