Deep Brain Stimulation (DBS) Frequency Effects on Gait in Parkinson's Disease(PD)
NCT ID: NCT00993291
Last Updated: 2012-01-27
Study Results
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View full resultsBasic Information
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COMPLETED
PHASE1/PHASE2
20 participants
INTERVENTIONAL
2009-11-30
2011-08-31
Brief Summary
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1. Stimulation at 60 Hertz (Hz) is associated with improved gait with increased stride length and faster time on the Stand walk sit test.
2. There is no worsening of the Unified Parkinson's Disease Rating Scale (UPDRS) at 60 Hz.
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Detailed Description
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Conditions
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Study Design
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NA
SINGLE_GROUP
TREATMENT
DOUBLE
Study Groups
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Baseline frequency
Baseline DBS frequency
Frequency change to 60 Hz
60 Hz stimulation for one hour, done twice over the 5 hour study period in a randomized blinded fashion.
Frequency change to 130 Hz
130 Hz Stimulation for one hour, done twice over the 5 hour study period in a randomized blinded fashion.
Interventions
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Frequency change to 60 Hz
60 Hz stimulation for one hour, done twice over the 5 hour study period in a randomized blinded fashion.
Frequency change to 130 Hz
130 Hz Stimulation for one hour, done twice over the 5 hour study period in a randomized blinded fashion.
Other Intervention Names
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Eligibility Criteria
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Inclusion Criteria
* Report a change in their gait.
* Be able to walk independently when off PD medications for 12-16 hours.
* Have a stable dose of PD medications for the prior three months .
* Not cognitively impaired, so as to give informed consent.
* MMSE \> 24.
ALL
No
Sponsors
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Vanderbilt University
OTHER
Responsible Party
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Fenna Phibbs
PI
Principal Investigators
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Fenna T Phibbs, MD
Role: PRINCIPAL_INVESTIGATOR
Vanderbilt Univeristy
Locations
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Vanderbilt University
Nashville, Tennessee, United States
Countries
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Other Identifiers
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090873
Identifier Type: -
Identifier Source: org_study_id
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