PRF Treatment for Patients With Chronic Lumbosacral Radicular Pain Compared to Conventional Medical Management

NCT ID: NCT00991237

Last Updated: 2013-10-24

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

45 participants

Study Classification

INTERVENTIONAL

Study Start Date

2010-02-28

Study Completion Date

2012-12-31

Brief Summary

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The purpose of the study is to evaluate the effect of PRF treatment adjacent to the lumbar dorsal root ganglion (DRG) of L5 or S1 in patients with a chronic lumbosacral radicular syndrome (LRS).

Prospective, single blinded, multicenter clinical trial.

Detailed Description

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Conditions

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Lumbosacral Radicular Syndrome

Keywords

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NRS GPE pain reduction quality of life

Study Design

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Allocation Method

NA

Intervention Model

SINGLE_GROUP

Primary Study Purpose

TREATMENT

Blinding Strategy

SINGLE

Investigators

Study Groups

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Pain reduction

Group Type EXPERIMENTAL

Pulsed Radiofrequency

Intervention Type OTHER

Pulsed Radiofrequency

Interventions

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Pulsed Radiofrequency

Pulsed Radiofrequency

Intervention Type OTHER

Other Intervention Names

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PRF

Eligibility Criteria

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Inclusion Criteria

* Symptoms more than 3 months 18,48
* Optimized conventional medical management at least for 1 month
* Pain radiating into the leg, up to the hallux (big toe) (L5) or little toe (S1)
* The pain in the leg dominates over a possible lumbalgia, the average pain in the leg measured 3 times a day, at predefined time points, over 4 consecutive days prior to inclusion should be more than 5 (NRS 10-point scale) 8
* Pattern of radiation suggestive for L5 or S1 pathology 49,50
* One or more positive neurological tests of nerve root tension or neurological deficit 51 ; straight leg raising test (SLRT), contralateral SLRT, motor reaction during SLRT and passive cervical flexion, motor reaction during passive cervical flexion while bending forward in standing position
* Capable of understanding the information relative to the treatment and procedure and willing to provide informed consent
* Capable of understanding and filling-out the questionnaires necessary for evaluation of the treatments
* Patients having undergone low back surgery like discectomy with or without laminectomy are allowed to participate in the study

Exclusion Criteria

* Patients younger than 18 years
* Malignant disorder or currently under treatment for a malignant disorder
* Previous lumbar fractures
* Proven myelum lesion or abnormalities in the central neurological structures
* Systemic or connective tissue diseases
* Diabetes mellitus type I
* Multiple sclerosis
* Coagulation disorders
* Pregnancy
* Conventional medical management less then 1 month
* Pain Catastrophizing Scale \> 45. When the patient has a higher score he/she will first be referred to a psychologist for consultation 52
* Leg pain due to localized hip or knee pathology
* Patients with a pacemaker or neurostimulator
* Patients previously treated with RF or PRF of the lumbar DRG
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Ziekenhuis Oost-Limburg

OTHER

Sponsor Role collaborator

Sint Jozef Hospital Bornem en Willebroek Belgium

UNKNOWN

Sponsor Role collaborator

Maastricht University Medical Center

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Maarten v Kleef, Prof. dr.

Role: PRINCIPAL_INVESTIGATOR

Maastricht UMC+

Locations

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Maastricht University Medical Centre

Maastricht, Limburg, Netherlands

Site Status

Countries

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Netherlands

Other Identifiers

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NL28367.068.09

Identifier Type: -

Identifier Source: org_study_id