Evoked Fields After Median and Ulnar Stimulation

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

COMPLETED

Total Enrollment

60 participants

Study Classification

OBSERVATIONAL

Study Start Date

2005-06-30

Study Completion Date

2007-06-30

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

In order to be able to study the effects of evoked fields with magnetoencephalography (MEG) in two groups of patients, comparison is made with a group of healthy volunteers.

Related Clinical Trials

Explore similar clinical trials based on study characteristics and research focus.

Cortical Neuroplasticity by Muscle Pain of Pain-induced Plasticity

NCT03354624

Nerve Growth Factor Exercise Motor Activity +2 more

COMPLETED NA

Transcranial Magnetic Stimulation and/or Neurofunctional Electrical Acupuncture in Myofascial Chronic Pain Patients

NCT02381171

Myofascial Pain Syndromes

UNKNOWN NA

A Neurofeedback Treatment for Chronic Musculoskeletal Pain

NCT03863847

Chronic Musculoskeletal Pain Tennis Elbow Musculoskeletal Pain +1 more

UNKNOWN NA

Effectiveness of Electro-acupuncture and Manual Therapy on Pain and Fucntion in Patients With Sciatica

NCT04764890

Sciatica Electroacupuncture Manual Therapy

UNKNOWN NA

Study on Magnetic Field Therapy to Improve Quality of Sleep and Reduction of Chronic Spine Pain

NCT00445133

Back Pain Neck Pain Sleep Initiation and Maintenance Disorders

UNKNOWN PHASE4

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

This study is directed at the (central and / or peripheral) mechanisms of pain and the cortical changes (plasticity) due to chronic non-malignant pain in two groups of patients and one healthy volunteer group.

The aim of the study is further to evaluate cortical processes by MEG (and fMRI, if feasible) to quantify and qualify the responses, localise the generators and study the effects of a pain therapy.

To search for patterns that may result in diagnostic criteria and have an indicative value for the treatment and the monitoring of the effects.

Finally the study not only intends to support clinical diagnosis but also to provide tools to monitor treatment and support the choice (algorithm) between SCS and SAN. An algorithm, facilitating decision making between these two treatments, will be promoted. It should also provide a clinical decision tool for the use of SAN

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Complex Regional Pain Syndromes

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

Review each arm or cohort in the study, along with the interventions and objectives associated with them.

Pain study Netherlands

20 healthy subjects 20 patients with a traumatic unilateral peripheral nerve injury 20 patients with CRPS I

Evoked fields before and after a local block (Xylocaine)

Intervention Type OTHER

MEG registration after electrical median and ulnar nerve stimulation in subjects and patients. In the patient group another MEG was performed after an anaesthetic block (1-2 ml Lidocaine 1%) at the site of the nerve injury producing a painfree state

Interventions

Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.

Evoked fields before and after a local block (Xylocaine)

MEG registration after electrical median and ulnar nerve stimulation in subjects and patients. In the patient group another MEG was performed after an anaesthetic block (1-2 ml Lidocaine 1%) at the site of the nerve injury producing a painfree state

Intervention Type OTHER

Other Intervention Names

Discover alternative or legacy names that may be used to describe the listed interventions across different sources.

All subjects were rated with the HC code, 1 to 20 All patients with nerve injury were rated with the A - code, 1 to 20 All patients with CRPS I were rated with the C - code, 1 to 20

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

CRPS I:

* (Absolute) functio laesa, secondary pain and cold sensations
* (Relative) abnormal skin colour, allodynia, hyperalgesia, hyperpathia, hyperhydrosis,oedema, increased nail growth, increased hair growth. (At least 4 need to be present).

CRPS II:

* All the previous but evidence of traumatic peripheral nerve injury.