Prevention of Intradialytic Hypotension in Acute Kidney Injury Patients

NCT ID: NCT00971971

Last Updated: 2009-09-07

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

40 participants

Study Classification

INTERVENTIONAL

Study Start Date

2005-10-31

Study Completion Date

2009-09-30

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

Intradialytic hypotension (IH) is a major complication during acute hemodialysis. The aim of this study was to evaluate the effects of dialysate temperature (DT) reduction with Na and ultrafiltration (UF) profiling on hemodynamics of critically ill acute kidney injury (AKI) patients submitted to sustained low-efficiency dialysis (SLED).

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Acute Kidney Injury Acute Renal Failure

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

Review each arm or cohort in the study, along with the interventions and objectives associated with them.

Control

Traditional SLED

Group Type NO_INTERVENTION

Standard SLED

Intervention Type PROCEDURE

Profiling

dialysate temperature reduction with Na and ultrafiltration (UF) profiling

Group Type EXPERIMENTAL

Dialysis

Intervention Type PROCEDURE

dialysate temperature (DT) reduction with Na and ultrafiltration (UF) profiling

Interventions

Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.

Dialysis

dialysate temperature (DT) reduction with Na and ultrafiltration (UF) profiling

Intervention Type PROCEDURE

Standard SLED

Intervention Type PROCEDURE

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

* Acute renal failure with a need of dialysis.

Exclusion Criteria

* Patients with basal serum creatinine \> 3 mgdL.
* Patients submitted to renal transplantation.
* Patients unlikely to survive.
* Declination in authorization to participation in the study.
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

Meet the organizations funding or collaborating on the study and learn about their roles.

Fundação de Amparo à Pesquisa do Estado de São Paulo

OTHER_GOV

Sponsor Role collaborator

Sao Jose do Rio Preto Medical School

OTHER

Sponsor Role lead

Responsible Party

Identify the individual or organization who holds primary responsibility for the study information submitted to regulators.

Associate Professor, Nephrology Division, São JOsé do Rio Preto Medical School

Locations

Explore where the study is taking place and check the recruitment status at each participating site.

São Jose do Rio Preto Medical School

São José do Rio Preto, São Paulo, Brazil

Site Status

Countries

Review the countries where the study has at least one active or historical site.

Brazil

Other Identifiers

Review additional registry numbers or institutional identifiers associated with this trial.

10727-6

Identifier Type: -

Identifier Source: org_study_id

More Related Trials

Additional clinical trials that may be relevant based on similarity analysis.

Outcome of ECMO and CRRT.
NCT05033509 COMPLETED
Ultrasound to Evaluate Acute Kidney Injury
NCT06241417 NOT_YET_RECRUITING