Adaptive Support Ventilation in the Weaning of COPD

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

PHASE4

Total Enrollment

97 participants

Study Classification

INTERVENTIONAL

Study Start Date

2007-04-30

Study Completion Date

2008-12-31

Brief Summary

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Adaptive support ventilation (ASV) is a closed loop ventilation mode that can act both as pressure support (PSV) and pressure controlled (PCV) ventilation. Weaning with ASV shows promising results mainly in post-cardiac surgery patients. The aim of this randomized controlled study was to test the hypothesis that weaning with ASV could reduce the weaning duration in patients with chronic obstructive pulmonary disease (COPD) when compared with PSV.

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Detailed Description

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Conditions

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Pulmonary Disease, Chronic Obstructive

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

SCREENING

Blinding Strategy

SINGLE

Participants

Study Groups

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Pressure support ventilation

Group Type ACTIVE_COMPARATOR

Comparison of two different modes for weaning from mechanical ventilation

Intervention Type PROCEDURE

Chronic obstructive pulmonary disease patients under mechanical ventilation were randomized to adaptive or pressure support ventilation modes when they met the weaning criteria.

Adaptive support ventilation

Group Type ACTIVE_COMPARATOR

Comparison of two different modes for weaning from mechanical ventilation

Intervention Type PROCEDURE

Chronic obstructive pulmonary disease patients under mechanical ventilation were randomized to adaptive or pressure support ventilation modes when they met the weaning criteria.

Interventions

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Comparison of two different modes for weaning from mechanical ventilation

Chronic obstructive pulmonary disease patients under mechanical ventilation were randomized to adaptive or pressure support ventilation modes when they met the weaning criteria.

Intervention Type PROCEDURE

Other Intervention Names

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weaning protocol

Eligibility Criteria

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Inclusion Criteria

* Diagnosis of COPD
* On invasive mechanical ventilation for at least 24 hours because of hypoxemic and/or hypercapnic respiratory failure

Exclusion Criteria

* Mechanical ventilation less then 24 hours (self extubation or death),
* Having a tracheotomy and
* COPD coexisted with severe cardiac or neurologic diseases.

Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No