Comparison Study of Biofoam Porous Metal Versus Allograft to Treat Adult Acquired Flatfoot

NCT ID: NCT00949897

Last Updated: 2013-03-13

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

WITHDRAWN

Clinical Phase

PHASE4

Study Classification

INTERVENTIONAL

Study Start Date

2009-03-31

Study Completion Date

2011-06-30

Brief Summary

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The purpose of this study is to compare the clinical and radiographic outcomes of a randomized, consecutive series of adult patients, with an acquired flatfoot, treated with a lateral column lengthening using an allograft bone wedge versus a titanium porous metal implant (Biofoam, Wright Medical).

Null hypothesis: At six months postoperatively, there is no difference in the degree of correction as measured by the talonavicular coverage angle between patients randomized to allograft and Biofoam.

Alternative hypothesis: At six months postoperatively, the degree of correction as measured by the talonavicular coverage angle will be less in patients randomized to allograft than the degree of correction in patients randomized to Biofoam.

Detailed Description

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Conditions

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Adult Acquired Flatfoot

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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Biofoam

Group Type ACTIVE_COMPARATOR

Biofoam

Intervention Type DEVICE

Device

Iliac Crest Allograft with locked plate

Group Type ACTIVE_COMPARATOR

Iliac Crest Allograft with locked plate

Intervention Type OTHER

Interventions

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Biofoam

Device

Intervention Type DEVICE

Iliac Crest Allograft with locked plate

Intervention Type OTHER

Other Intervention Names

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510(k) Number: K073535 Iliac Crest Allograft

Eligibility Criteria

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Inclusion Criteria

* Ages 25-75
* Unresponsive to conservative treatment
* Patient with acquired flatfoot deformity, who is a candidate for lateral column lengthening (Stage IIB) = (greater than \> 40% uncoverage of talar head by navicular on standing AP radiograph)

Exclusion Criteria

* Less than 25 years of age and greater than 75 years
* Pre-existing infection
* Peripheral neuropathy
* Charcot arthropathy
* Peripheral vascular disease
* Rhematoid Arthritis (RA) or inflammatory arthropathy
* Metal allergy or sensitivity to metal
Minimum Eligible Age

25 Years

Maximum Eligible Age

75 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Stryker Trauma and Extremities

INDUSTRY

Sponsor Role collaborator

OrthoCarolina Research Institute, Inc.

OTHER

Sponsor Role lead

Responsible Party

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OrthoCarolina Research Institute, Inc.

Principal Investigators

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Robert B Anderson, MD

Role: PRINCIPAL_INVESTIGATOR

OrthoCarolina, P.A.

Locations

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OrthoCarolina, P.A.

Charlotte, North Carolina, United States

Site Status

Countries

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United States

Other Identifiers

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120813B

Identifier Type: -

Identifier Source: org_study_id

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