The Early Origins of Cardiovascular Disease

NCT ID: NCT00923039

Last Updated: 2009-06-18

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Total Enrollment

200 participants

Study Classification

OBSERVATIONAL

Study Start Date

2009-06-30

Brief Summary

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Small body size at birth, slow weight gain during infancy and increase in body mass index after 2 years are independent risk factors for cardiovascular disease and the metabolic syndrome. There is a large gap in our understanding of how early growth affects the cardiovascular system. Possible mechanisms include alterations in body composition, in cardiac structure, in vascular function, in renal function and epigenetic processes.

The Objective is to determine how size at birth and growth during infancy and childhood affect: body composition, cardiac structure and function, vascular and endothelial function, renal function, metabolic status and transcriptional and epigenetic characteristics.

Detailed Description

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Conditions

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Cardiovascular Disease

Study Design

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Observational Model Type

COHORT

Study Time Perspective

RETROSPECTIVE

Study Groups

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Exposed/ Not exposed

No interventions assigned to this group

Eligibility Criteria

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Inclusion Criteria

* Male and female volunteers students aged between 18-25 years old
* Having growth records

Exclusion Criteria

* If young women subject without contraception,or pregnant
Minimum Eligible Age

18 Years

Maximum Eligible Age

25 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Danone Institute International

OTHER

Sponsor Role lead

Responsible Party

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Danone Institute International

Locations

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CIC-UPCET Hopital de la Timone Bat F

Marseille, , France

Site Status

Countries

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France

Central Contacts

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Umberto SIMEONI, MD,PhD

Role: CONTACT

33 (0)4 91 38 40 30

Olivier BLIN, MD,PhD

Role: CONTACT

33 (0)4 91 38 75 63

Facility Contacts

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Olivier BLIN, MD

Role: primary

+33 (0) 491 387 563

Other Identifiers

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NU 304

Identifier Type: -

Identifier Source: org_study_id

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