Measurement of Recirculation During Venovenous Extracorporeal Membrane Oxygenation (VV ECMO)

NCT ID: NCT00920062

Last Updated: 2016-05-27

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

16 participants

Study Classification

OBSERVATIONAL

Study Start Date

2007-06-30

Study Completion Date

2013-06-30

Brief Summary

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This study is to test the usefulness of ultrasound dilution recirculation measurements in patients receiving venovenous extracorporeal membrane oxygenation as therapy. The ultrasound dilution measurements determine the efficiency of support provided by venovenous extracorporeal membrane oxygenation. At the present time there are no other devices available to make recirculation measurements.

Detailed Description

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At the present time there are no devices available to measure recirculation in patients on venovenous extracorporeal membrane oxygenation. The study uses an external monitor, laptop computer, clamp on flowsensors and ultrasound dilution technology to measure blood flow. Measurements are made by injecting 0.5 - 1 ml/kg of sterile isotonic saline into the patient's extracorporeal circuit. The subject will be monitored throughout the measurements. The measurements will be coordinated with the regular care of the patient and their extracorporeal circuit.

Conditions

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Venovenous Extracorporeal Membrane Oxygenation Recirculation

Study Design

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Study Time Perspective

PROSPECTIVE

Eligibility Criteria

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Inclusion Criteria

* Patients between 0 and 21 years of age
* Patients receiving venovenous extracorporeal membrane oxygenation as treatment.

Exclusion Criteria

* Patients over 21 years of age
* Patients not receiving venovenous extracorporeal membrane oxygenation.
Maximum Eligible Age

21 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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National Heart, Lung, and Blood Institute (NHLBI)

NIH

Sponsor Role collaborator

Transonic Systems Inc.

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Nikolai M Krivitski, PhD, DSc

Role: PRINCIPAL_INVESTIGATOR

Transonic Systems Inc.

Bonnie L Marr, MD

Role: PRINCIPAL_INVESTIGATOR

Crouse Hospital

Locations

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Crouse Hospital

Syracuse, New York, United States

Site Status

Countries

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United States

References

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Clements D, Primmer J, Ryman P, Marr B, Searles B, Darling E. Measurements of recirculation during neonatal veno-venous extracorporeal membrane oxygenation: clinical application of the ultrasound dilution technique. J Extra Corpor Technol. 2008 Sep;40(3):184-7.

Reference Type BACKGROUND
PMID: 18853830 (View on PubMed)

Other Identifiers

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2R44HL082022-02

Identifier Type: NIH

Identifier Source: secondary_id

View Link

TSI-C-HCE101-3A-H

Identifier Type: -

Identifier Source: org_study_id

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