Estimation of Pulmonary Vascular Resistance by Contrast Echocardiography

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

38 participants

Study Classification

INTERVENTIONAL

Study Start Date

2010-04-30

Study Completion Date

2012-07-31

Brief Summary

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An echocardiogram using Definity contrast can provide the same information as the standard right heart catheterization.

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Detailed Description

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Conditions

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Pulmonary Arterial Hypertension

Study Design

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Allocation Method

NA

Intervention Model

SINGLE_GROUP

Primary Study Purpose

DIAGNOSTIC

Blinding Strategy

NONE

Study Groups

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2D doppler echo with Definity solution

Study subjects will already be scheduled for right heart catheterization to diagnose pulmonary hypertension. Prior to the catheterization, each subject will have a 2D doppler echocardiogram with Definity solution as well.

Group Type EXPERIMENTAL

2D doppler echo with Definity solution

Intervention Type PROCEDURE

Correlate right heart catheterization results with results from 2D doppler echo with Definity Solution

Interventions

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2D doppler echo with Definity solution

Correlate right heart catheterization results with results from 2D doppler echo with Definity Solution

Intervention Type PROCEDURE

Other Intervention Names

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Definity solution

Eligibility Criteria

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Inclusion Criteria

* Adult patients scheduled to undergo right heart catheterization at the George Washington University Hospital

Exclusion Criteria

* Patients with known or suspected right-to-left bi-directional or transient right-to-left shunts or pulmonary arteriovenous malformations, previously documented moderate to severe tricuspid regurgitation or moderate to severe pulmonary regurgitation, evidence of right ventricular hypokinesis, or prior adverse reaction to Definity or hypersensitivity to perflutren

Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No