Gut Hormone Response, Appetite and Intestinal Transit Time in Good and Poor Weight Responders After Gastric Bypass

NCT ID: NCT00908973

Last Updated: 2012-03-20

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

46 participants

Study Classification

OBSERVATIONAL

Study Start Date

2009-05-31

Study Completion Date

2011-12-31

Brief Summary

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The aim of the study is to describe differences in meal-stimulated gut hormone response, appetite and intestinal transit time between good and poor responders 1-2 years after Gastric Bypass surgery for obesity.

Detailed Description

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Conditions

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Obesity

Study Design

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Observational Model Type

CASE_CONTROL

Study Time Perspective

PROSPECTIVE

Study Groups

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Good responders

Excess weight loss of \> 60% 1 year after gastric bypass surgery

No interventions assigned to this group

Poor responders

Excess weight loss of =\< 50% 1 year after gastric bypass surgery

No interventions assigned to this group

Lean controls

Non-gastric bypass operated lean individuals, matched for age and sex

No interventions assigned to this group

Eligibility Criteria

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Inclusion Criteria

* Age 20-60 years
* Completed laparoscopic gastric bypass surgery without complications (cases)
* No previous gastric bypass surgery (controls)

Exclusion Criteria

* Diabetes
* Disease or treatment interfering with appetite or gastrointestinal motility
* Pregnancy or breastfeeding
* Excess weight loss 1 year after gastric bypass \> 50% and =\< 60% (cases)
Minimum Eligible Age

20 Years

Maximum Eligible Age

60 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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University of Copenhagen

OTHER

Sponsor Role collaborator

Novo Nordisk A/S

INDUSTRY

Sponsor Role collaborator

Hvidovre University Hospital

OTHER

Sponsor Role lead

Responsible Party

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Carsten Dirksen

MD PhD student

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Carsten Dirksen, MD

Role: PRINCIPAL_INVESTIGATOR

Dept. of Endocrinology, Hvidovre University Hospital, Hvidovre, Copenhagen, Denmark

Locations

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Department of Endocrinology at Hvidovre University Hospital

Hvidovre, Copenhagen, Denmark

Site Status

Countries

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Denmark

Other Identifiers

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RnonR

Identifier Type: -

Identifier Source: org_study_id

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