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The Effect of Gastric Bypass Surgery on Gut Hormones Related to Bone Remodeling and Intestinal Growth.

NCT ID: NCT01700686

Last Updated: 2014-12-17

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

18 participants

Study Classification

OBSERVATIONAL

Study Start Date

2011-10-31

Study Completion Date

2014-09-30

Brief Summary

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The overall purpose is to explore the link between the gut and the bones by investigating meal stimulated changes in the blood level of a number of hormones and markers related to intestinal growth and bone turnover in patients undergoing surgery for obesity (gastric bypass). The hormones will be measured in blood samples taken before and after surgery. The results are compared with changes in body weight and body composition as measured by DEXA scanning.

Detailed Description

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Conditions

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Obesity Bone Loss

Study Design

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Observational Model Type

CASE_ONLY

Study Time Perspective

PROSPECTIVE

Study Groups

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Obese subjects

Meal test and dexa scan

Meal test and dexa scan

Intervention Type OTHER

Body composition is determined by whole body deca scan and bone mineral density is determined dy dexa scans of the lumbar spine and the proximal femur.

Interventions

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Meal test and dexa scan

Body composition is determined by whole body deca scan and bone mineral density is determined dy dexa scans of the lumbar spine and the proximal femur.

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Caucasians fulfilling the criteria for laparoscopic gastric bypass.
* BMI\>40kg/m2.

Exclusion Criteria

* Pregnancy
* Chronic obstructive pulmonary disease
* Diabetes mellitus
* Chronic inflammatory bowel disease
* Major psychiatric disorder
* Drug abuse
Minimum Eligible Age

18 Years

Maximum Eligible Age

65 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Zealand University Hospital

OTHER

Sponsor Role collaborator

University of Copenhagen

OTHER

Sponsor Role lead

Responsible Party

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Bolette Hartmann

PhD

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Bolette Hartmann, PhD

Role: PRINCIPAL_INVESTIGATOR

University of Copenhagen

Locations

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Hospital of Roskilde-Koege, The University of Copenhagen

Koege, , Denmark

Site Status

Countries

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Denmark

Other Identifiers

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GBPK

Identifier Type: -

Identifier Source: org_study_id