Evaluation of Different Continuous Positive Airway Pressure (CPAP) Systems in Patients With Acute Respiratory Failure

NCT ID: NCT00876473

Last Updated: 2015-04-28

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

30 participants

Study Classification

OBSERVATIONAL

Study Start Date

2009-04-30

Study Completion Date

2014-01-31

Brief Summary

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The aim of this study is to evaluate the performance, the tolerability and the efficacy on gas-exchange of different CPAP (Continuous Positive Airway Pressure) systems.

Detailed Description

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Three CPAP systems are studied for each patient at the same level of PEEP: 1) continuous high-flow CPAP with fixed value PEEP valve; 2) continuous high-flow CPAP with Boussignac PEEP valve; 3) demand flow CPAP, supplied by a ventilator.

Conditions

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Acute Respiratory Failure

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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1

Acute Respiratory Failure patients

CPAP system

Intervention Type PROCEDURE

Evaluating the effects of different CPAP systems on respiratory mechanics, respiratory effort and gas-exchange

CPAP systems:

Continuous high-flow CPAP with fixed value PEEP valve

Continuous high-flow CPAP with Boussignac valve

Demand flow CPAP supplied by ventilator

Interventions

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CPAP system

Evaluating the effects of different CPAP systems on respiratory mechanics, respiratory effort and gas-exchange

CPAP systems:

Continuous high-flow CPAP with fixed value PEEP valve

Continuous high-flow CPAP with Boussignac valve

Demand flow CPAP supplied by ventilator

Intervention Type PROCEDURE

Eligibility Criteria

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Inclusion Criteria

* Intubated-tracheostomized subjects receiving CPAP during the weaning from invasive mechanical ventilation

Exclusion Criteria

* Hemodynamic instability
* Barotrauma
* Severe myopathy
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Policlinico Hospital

OTHER

Sponsor Role lead

Responsible Party

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Davide Chiumello

MD

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Davide Chiumello, MD

Role: PRINCIPAL_INVESTIGATOR

Policlinico Hospital

Locations

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Policlinico Hospital

Milan, , Italy

Site Status

Countries

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Italy

Other Identifiers

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590

Identifier Type: -

Identifier Source: org_study_id

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