Magnetic Resonance Imaging (MRI) Study of the Hippocampus After Infarction in the Territory of the Middle Cerebral Artery

NCT ID: NCT00867581

Last Updated: 2009-03-24

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Total Enrollment

80 participants

Study Classification

OBSERVATIONAL

Study Start Date

2008-09-30

Brief Summary

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The purpose of this study is to observe delayed neuronal death of hippocampus after middle cerebral artery infarction in human beings.

Detailed Description

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40 patients with middle cerebral artery infarction and 40 healthy volunteers will be observed. All of them will receive MRI scan and the assessment of the neuropsychological function (MMSE, AVLT, HAMD) intending to observe delayed neuronal death of hippocampus after middle cerebral artery infarction in human beings.

Conditions

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Ischemic Stroke

Study Design

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Observational Model Type

CASE_CONTROL

Study Time Perspective

CROSS_SECTIONAL

Study Groups

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1

chronic-stage patients after infarction in the territory of unilateral middle cerebral artery

No interventions assigned to this group

2

age, sex and risk factor matched volunteers without ischemic stroke

No interventions assigned to this group

Eligibility Criteria

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Inclusion Criteria

* Clinical diagnosis of middle cerebral artery infarction
* At least six months from the stroke
* Must be able to measure his(her) neuropsychologic function (by MMSE, AVLT)

Exclusion Criteria

* Unable to undergo examinations due to disturbances of consciousness or medical conditions
* Severe dementia, apraxia, disturbances of sensation or perception
* Serious complications including severe heart failure, hepatic dysfunction, renal insufficiency,or shock
* Parkinson's disease, malignant tumor, autoimmune diseases
Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Huazhong University of Science and Technology

OTHER

Sponsor Role lead

Responsible Party

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Department of Neurology of Tongji Hospital, Huazhong University of Sci. and Tec

Principal Investigators

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Wei Wang, Doctor

Role: PRINCIPAL_INVESTIGATOR

Tongji Hospital

Locations

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Department of Neurology of Tongji Hospital, Huazhong University of Science and Technology

Wuhan, Hubei, China

Site Status RECRUITING

Countries

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China

Central Contacts

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Wei Wang, Doctor

Role: CONTACT

86-027-8366-3648

Facility Contacts

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Wei Wang, Doctor

Role: primary

86-027-8366-3648

Other Identifiers

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30725019-2

Identifier Type: -

Identifier Source: org_study_id

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