Flow Proportional Pressure Support in Volunteers

NCT ID: NCT00866541

Last Updated: 2009-03-20

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Clinical Phase

NA

Total Enrollment

20 participants

Study Classification

INTERVENTIONAL

Study Start Date

2009-01-31

Brief Summary

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Flow proportional pressure support (FPPS) is a new mode of spontaneous breathing assistance. In patients with increased respiratory resistance the role of FPPS in comparison with the pressure support assist breathing mode is still unclear. In this study the investigators evaluate objective and subjective measured data in healthy volunteers with artificial increased resistance and FPPS breathing assistance.

Detailed Description

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Conditions

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Healthy

Study Design

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Allocation Method

NA

Intervention Model

SINGLE_GROUP

Primary Study Purpose

BASIC_SCIENCE

Blinding Strategy

DOUBLE

Participants Investigators

Study Groups

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volunteers

artificial increased respiratory resistance

Group Type EXPERIMENTAL

artificial increased resistance (flow proportional pressure support)

Intervention Type DEVICE

respiratory resistance is increased by interpose of an artificial resistance tool in the in- and expiratory airways of the mechanical respirator

Interventions

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artificial increased resistance (flow proportional pressure support)

respiratory resistance is increased by interpose of an artificial resistance tool in the in- and expiratory airways of the mechanical respirator

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

* age over 18 years
* ASA I and II

Exclusion Criteria

* refusal of written informed consent
* chronic respiratory or cardiac diseases
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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University Hospital Freiburg

OTHER

Sponsor Role lead

Responsible Party

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University Medical Center Freiburg

Principal Investigators

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Daniel Steinmann, MD

Role: PRINCIPAL_INVESTIGATOR

University Medical Center Freiburg

Locations

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University Medical Center Freiburg

Freiburg im Breisgau, , Germany

Site Status RECRUITING

Countries

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Germany

Central Contacts

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Daniel Steinmann, MD

Role: CONTACT

0049 761 270 2329

Facility Contacts

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Daniel Steinmann, MD

Role: primary

0049 761 270 2329

References

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Mols G, Vetter T, Haberthur C, Geiger K, Guttmann J. Breathing pattern and perception at different levels of volume assist and pressure support in volunteers. Crit Care Med. 2001 May;29(5):982-8. doi: 10.1097/00003246-200105000-00018.

Reference Type BACKGROUND
PMID: 11378608 (View on PubMed)

Mols G, von Ungern-Sternberg B, Rohr E, Haberthur C, Geiger K, Guttmann J. Respiratory comfort and breathing pattern during volume proportional assist ventilation and pressure support ventilation: a study on volunteers with artificially reduced compliance. Crit Care Med. 2000 Jun;28(6):1940-6. doi: 10.1097/00003246-200006000-00042.

Reference Type BACKGROUND
PMID: 10890645 (View on PubMed)

Mols G, Rohr E, Benzing A, Haberthur C, Geiger K, Guttmann J. Breathing pattern associated with respiratory comfort during automatic tube compensation and pressure support ventilation in normal subjects. Acta Anaesthesiol Scand. 2000 Mar;44(3):223-30. doi: 10.1034/j.1399-6576.2000.440302.x.

Reference Type BACKGROUND
PMID: 10714832 (View on PubMed)

Guttmann J, Bernhard H, Mols G, Benzing A, Hofmann P, Haberthur C, Zappe D, Fabry B, Geiger K. Respiratory comfort of automatic tube compensation and inspiratory pressure support in conscious humans. Intensive Care Med. 1997 Nov;23(11):1119-24. doi: 10.1007/s001340050467.

Reference Type BACKGROUND
PMID: 9434916 (View on PubMed)

Other Identifiers

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327/07

Identifier Type: -

Identifier Source: org_study_id

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