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Transpulmonary Pressure and Airway Pressure Release Ventilation (APRV).

NCT ID: NCT02866513

Last Updated: 2017-11-14

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

20 participants

Study Classification

INTERVENTIONAL

Study Start Date

2016-02-29

Study Completion Date

2017-03-31

Brief Summary

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Mechanical ventilation can induce pulmonary lesions called ventilator induced lung injury (VILI). High levels of Transpulmonary pressure is one of the most important mechanism of VILI during the use of mechanical ventilation. The use of bilevel pressure ventilator modes like APRV could generate high levels of transpulmonary pressure.

The aim of this study is to evaluate the variations of transpulmonary pressure during the use of APRV by clinicians

Detailed Description

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Conditions

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Patient Mechanically Ventilated With APRV Mode

Study Design

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Allocation Method

NA

Intervention Model

SINGLE_GROUP

Primary Study Purpose

OTHER

Blinding Strategy

NONE

Study Groups

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Patient mechanically ventilated with APRV mode

Group Type OTHER

evaluate the variations of transpulmonary pressure during the use of APRV by clinicians.

Intervention Type OTHER

Interventions

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evaluate the variations of transpulmonary pressure during the use of APRV by clinicians.

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Adult
* Patient mechanically ventilated for more than 48 H for acute respiratory failure
* Decision to use of the APRV mode by clinicians in charge of the patient

Exclusion Criteria

\- Contraindication for the use of a nasogastric tube
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Assistance Publique Hopitaux De Marseille

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Urielle DESALBRES

Role: STUDY_DIRECTOR

Assistance Publique Hôpitaux de Marseille

Locations

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Assistance Publique Hôpitaux de Marseille hôpital de la Timone

Marseille, , France

Site Status

Countries

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France

Other Identifiers

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2015-19

Identifier Type: -

Identifier Source: org_study_id