SS-GCC1- Screening Study of Genetic Changes in Colorectal Cancer

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Total Enrollment

3750 participants

Study Classification

OBSERVATIONAL

Study Start Date

2008-11-30

Study Completion Date

2021-07-01

Brief Summary

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the principal research objective is to form a database of tissue samples from patients with colorectal (bowel) cancer. The tissue samples that will be used for this research will have already been taken for diagnostic or therapeutic reasons. We will also be asking for consent for a research blood sample. The database will be used to improve our understanding of the molecular genetics and gene expression patterns in colorectal cancer.

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Detailed Description

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All patients at the Royal Marsden with a diagnosis of colorectal cancer will be eligible to enter this study. This will include patients both with early and advanced disease, provided they give informed consent. They will give written consent to participate, to include consent for analysis of existing tumour tissue and consent for collection of demographic and clinicopathological data relating to their case and its future outcome, and consent for a blood sample to be taken for research purposes. Additionally, old samples of material surplus to clinical requirements may be collected without specific consent if there is no possibility that it would affect the patient's interest (eg the patient has died).

Conditions

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Colorectal Cancer

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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No treatment

confirmed diagnosis of colorectal carcinoma

No interventions assigned to this group

Eligibility Criteria

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Inclusion Criteria

* adults who have a terminal illness
* 18 and over
* confirmed diagnosis of colorectal carcinoma
* ability to give informed consent
* paraffin embedded histological material available for analysis