Spinal Mepivicaine With Fentanyl for Outpatient Knee Arthroscopy

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

34 participants

Study Classification

INTERVENTIONAL

Study Start Date

2008-08-31

Study Completion Date

2009-05-31

Brief Summary

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The purpose of this study is to determine if the addition of intrathecal fentanyl to low dose mepivacaine spinal anesthesia provides adequate surgical anesthesia with shorter duration of motor blockade.

It is hypothesized that lower doses of spinal mepivacaine when combined with fentanyl will result in adequate surgical block for knee arthroscopy surgery with faster recovery and discharge compared to mepivacaine alone.

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Detailed Description

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Conditions

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Knee Arthroscopy

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

TRIPLE

Participants Investigators Outcome Assessors

Study Groups

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1

Mepivicaine for spinal anesthesia

Group Type ACTIVE_COMPARATOR

Mepivacaine without fentanyl

Intervention Type DRUG

45 mg 1.5% mepivacaine injection for spinal anesthesia

2

Mepivacaine with Fentanyl for spinal anesthesia

Group Type EXPERIMENTAL

Mepivacaine with Fentanyl

Intervention Type DRUG

10 micrograms fentanyl with 30 mg 1.5% mepivacaine injection for spinal anesthesia

Interventions

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Mepivacaine without fentanyl

45 mg 1.5% mepivacaine injection for spinal anesthesia

Intervention Type DRUG

Mepivacaine with Fentanyl

10 micrograms fentanyl with 30 mg 1.5% mepivacaine injection for spinal anesthesia

Intervention Type DRUG

Eligibility Criteria

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Inclusion Criteria

1. Patients having unilateral arthroscopic surgery of the knee;
2. ASA I-III status;
3. Age 18-80 years;
4. BMI\< 35.

Exclusion Criteria

1. Patients who have previous history of hypersensitivity to local anesthetics or contraindications for spinal anesthesia (i.e. bleeding diathesis, coagulopathy);
2. Patients with radiating low back pain and neurological deficits in lower extremities;
3. Patients who are incapable of giving an informed consent.

Minimum Eligible Age

18 Years

Maximum Eligible Age

80 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No