Effects of a Peripheral Nerve Block on Biomarkers of Pain and Inflammation

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

15 participants

Study Classification

INTERVENTIONAL

Study Start Date

2007-10-31

Study Completion Date

2008-07-31

Brief Summary

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The purpose of this study is to determine the effect of a local anesthetic nerve block on markers of inflammation and pain after a sunburn. This is important because it may provide information regarding the way that nerve blocks help with the treatment of pain and in particular provide preemptive analgesia.

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Complication of Anesthesia

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Detailed Description

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Conditions

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Pain

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

CROSSOVER

Primary Study Purpose

PREVENTION

Blinding Strategy

DOUBLE

Interventions

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femoral nerve block

Intervention Type PROCEDURE

Eligibility Criteria

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Inclusion Criteria

Inclusion Criteria:1. Between 18 and 50 years of age 2. Fluent in English language 3. Provide written informed consent 4.

Exclusion Criteria

Skin pigmentation type II or III\
 Exclusion Criteria:1. Current use of prescription drugs interfering with study objective 2. Use of over-the-counter analgesic/anti-inflammatory drugs within 48h of study participation 3. Current acute or chronic pain conditions 4. Significant medical conditions including psychiatric, neurological, and dermatological diseases 5. Pregnancy 6. Allergies to study drug(s) 7. Concomitant participation in other study protocol

Minimum Eligible Age

18 Years

Maximum Eligible Age

50 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No