Ultrasound-Guided Block of the Lateral Femoral Cutaneous Nerve in Pediatric Patients

NCT ID: NCT01500655

Last Updated: 2016-12-06

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

19 participants

Study Classification

INTERVENTIONAL

Study Start Date

2008-04-30

Study Completion Date

2013-09-30

Brief Summary

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The purpose of this study is to determine whether either a peripheral nerve block under ultrasound (u/s) guidance of the lateral femoral cutaneous nerve (LFCN), versus an u/s guided block of the nerve followed by continuous catheter infusion of local anesthetic, offers better post-operative analgesia in pediatric burn patients undergoing reconstructive surgery, than the current analgesic regimen of subcutaneous local anesthetic infiltration.

Eligible subject, pediatric patients having reconstructive surgery for burns, having skin graft donor sites of the lateral thighs, will be randomized into three groups: control (having local infiltration of site), ultrasound guided nerve block, or ultrasound guided nerve block with catheter placement --fascia iliac.

Post-operative comfort will be assessed over the next 48 hours.

Detailed Description

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Conditions

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Burns

Keywords

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burn skin graft donor site analgesia for donor site

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

FACTORIAL

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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Catheter

An ultrasound guided block of the LFCN is performed, followed by the placement of a catheter underneath the fascia iliaca.

Group Type EXPERIMENTAL

Regional nerve block

Intervention Type PROCEDURE

a block of the lateral femoral cutaneous nerve is performed under ultrasound guidance. For LFCN block, ropivacaine 0.2% will be used. Dose will be 20 ml, unless patient weighs less than 20 kg, in which case volume will be equal to patient's weight in kilograms.

Catheter

Intervention Type PROCEDURE

After an ultrasound guided nerve block is performed a catheter is placed under the fascia iliaca and an infusion of ropivacaine 0.2% running at 0.15 ml/kg/hour is administered for 48 hours.

Ultrasound guided LFCN block

An ultrasound guided regional nerve block --using ropivacaine 0.2%-- will be performed around the lateral femoral cutaneous nerve (LFCN).

Group Type EXPERIMENTAL

Regional nerve block

Intervention Type PROCEDURE

a block of the lateral femoral cutaneous nerve is performed under ultrasound guidance. For LFCN block, ropivacaine 0.2% will be used. Dose will be 20 ml, unless patient weighs less than 20 kg, in which case volume will be equal to patient's weight in kilograms.

Control

This group gets the current standard of care--the donor site is infiltrated with 0.25% bupivacaine.

Group Type NO_INTERVENTION

No interventions assigned to this group

Interventions

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Regional nerve block

a block of the lateral femoral cutaneous nerve is performed under ultrasound guidance. For LFCN block, ropivacaine 0.2% will be used. Dose will be 20 ml, unless patient weighs less than 20 kg, in which case volume will be equal to patient's weight in kilograms.

Intervention Type PROCEDURE

Catheter

After an ultrasound guided nerve block is performed a catheter is placed under the fascia iliaca and an infusion of ropivacaine 0.2% running at 0.15 ml/kg/hour is administered for 48 hours.

Intervention Type PROCEDURE

Eligibility Criteria

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Inclusion Criteria

* going for reconstructive surgery requiring split thickness skin graft
* patient's donor site will be in distribution of lateral femoral cutaneous nerve
* age \>=2 and \<22
* patient emotionally/intellectually able to describe intensity of post-op pain using VAS or Wong- Baker faces scale.

Exclusion Criteria

* potential block/catheter site infected or burned.
* intolerance/allergy to local anesthetics
* BMI \> 30
* American Society of Anesthesiologists (ASA) score \> 2
Minimum Eligible Age

2 Years

Maximum Eligible Age

21 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Massachusetts General Hospital

OTHER

Sponsor Role lead

Responsible Party

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Erik S. Shank, MD

Staff Physician: Pediatric Anesthesiologist

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Erik S Shank, MD

Role: PRINCIPAL_INVESTIGATOR

Partners Health Care

Locations

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Shriners Hospital for Children

Boston, Massachusetts, United States

Site Status

Countries

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United States

Other Identifiers

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2008P001944

Identifier Type: -

Identifier Source: org_study_id