Efficacy of Fish Oil Supplementation on Cognition in MCI Patients and the Influence of the APOE4 Allele
NCT ID: NCT00746005
Last Updated: 2011-01-12
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.
COMPLETED
NA
40 participants
INTERVENTIONAL
2008-10-31
2011-01-31
Brief Summary
Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.
Related Clinical Trials
Explore similar clinical trials based on study characteristics and research focus.
Preliminary Study of Fish Oil and Dementia
NCT00628017
DHA (Docosahexaenoic Acid), an Omega 3 Fatty Acid, in Slowing the Progression of Alzheimer's Disease
NCT00440050
Lipoic Acid and Omega-3 Fatty Acids for Alzheimer's Disease
NCT01058941
Omega-3 Fatty Acids and/or Multi-domain Intervention in the Prevention of Age-related Cognitive Decline
NCT00672685
The Effects of Efalex Active 50+ on Cognitive Performance, Well-being and Cerebral Hemodynamics in Healthy Older Adults
NCT01185379
Detailed Description
Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.
Conditions
See the medical conditions and disease areas that this research is targeting or investigating.
Study Design
Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.
RANDOMIZED
PARALLEL
PREVENTION
QUADRUPLE
Study Groups
Review each arm or cohort in the study, along with the interventions and objectives associated with them.
1
3 g EPA-DHA
fish oil
3 g fish oil (3078 mg) total EPA 1512 mg and total DHA 1026 mg
2
Placebo: sunflower oil
placebo, sunflower oil
3 g of sunflower oil
Interventions
Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.
fish oil
3 g fish oil (3078 mg) total EPA 1512 mg and total DHA 1026 mg
placebo, sunflower oil
3 g of sunflower oil
Eligibility Criteria
Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.
Inclusion Criteria
* Diagnosed as having amnestic MCI: based on specific memory disturbances (cut-off of 1 sd, single or multiple domain amnestic MCI, according to Busse A et al37)
* Presence of a principal caregiver willing to assist for a successful participation
* Informed consent signed
Exclusion Criteria
* Consumption of fish more than 2 times/week
* Current use of dementia (Alzheimer) medication
* Current use of acenocoumarol or other anti-thrombotic drugs (because of the high dose of fish oil)
* Serious liver disease
* Use of more than 4 glasses of alcohol per day
* Unable to participate as judged by the responsible medical physician
* Allergy to fish(oil)
* Swallowing problems
* Participation in another clinical trial less than 2 months before the start of the trial or at the same time
ALL
No
Sponsors
Meet the organizations funding or collaborating on the study and learn about their roles.
Radboud University Medical Center
OTHER
Wageningen University
OTHER
Responsible Party
Identify the individual or organization who holds primary responsibility for the study information submitted to regulators.
Wageningen University
Locations
Explore where the study is taking place and check the recruitment status at each participating site.
Ziekenhuis Gelderse Vallei
Ede, Gelderland, Netherlands
Radboud University Medical Center
Nijmegen, Gelderland, Netherlands
Countries
Review the countries where the study has at least one active or historical site.
Related Links
Access external resources that provide additional context or updates about the study.
Related Info
Other Identifiers
Review additional registry numbers or institutional identifiers associated with this trial.
2008/112
Identifier Type: -
Identifier Source: org_study_id
More Related Trials
Additional clinical trials that may be relevant based on similarity analysis.