Absorption Kinetics of Polyphenols in Angel's Plant (Angelica Keiskei)

NCT ID: NCT00721643

Last Updated: 2017-04-25

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

EARLY_PHASE1

Total Enrollment

10 participants

Study Classification

INTERVENTIONAL

Study Start Date

2008-07-31

Study Completion Date

2010-12-31

Brief Summary

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The absorption kinetics of polyphenols in angel's plant (Angelica keiskei), which is a dark green leafy vegetable rich in antioxidant nutrients, will be determined in older adults in this pilot study.

Detailed Description

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Conditions

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Oxidative Stress

Study Design

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Allocation Method

NON_RANDOMIZED

Intervention Model

SINGLE_GROUP

Primary Study Purpose

BASIC_SCIENCE

Blinding Strategy

NONE

Study Groups

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1

Healthy control, 5g dry power of angel's plant (Angelica keiskei)

Group Type EXPERIMENTAL

angel's plant (Angelica keiskei)

Intervention Type DIETARY_SUPPLEMENT

Healthy control, one time dose of 5g dry power of Angelica keiskei

2

Metabolic syndrome, 5g dry powder of angel's plant (Angelica keiskei)

Group Type EXPERIMENTAL

Angel's plant (Angelica keiskei)

Intervention Type DIETARY_SUPPLEMENT

Metaboic syndrome subjects, one time dose of 5g dry powder of angel's plant (Angelica keiskei)

Interventions

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angel's plant (Angelica keiskei)

Healthy control, one time dose of 5g dry power of Angelica keiskei

Intervention Type DIETARY_SUPPLEMENT

Angel's plant (Angelica keiskei)

Metaboic syndrome subjects, one time dose of 5g dry powder of angel's plant (Angelica keiskei)

Intervention Type DIETARY_SUPPLEMENT

Eligibility Criteria

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Inclusion Criteria

* Healthy subjects (\>60 yr, n=5)
* subjects with metabolic syndrome (\>60 yr, n=5)
* Subjects who has

* high fasting plasma glucose (\>5.6 mmol/L),
* central obesity (waist-hip ratio, \>0.9 for men, \>0.85 for women)
* either high blood pressure (\>130/85 mmHg) or high triacylglycerol (\>1.7 mmol/L) will be selected to have metabolic syndrome.
* normal hematological parameters, normal serum albumin, normal liver function, and normal kidney function
* no history of smoking or alcoholism.

Exclusion Criteria

* consume \>7 alcoholic drinks/wk
* taking cholesterol medication or hormone replacement
Minimum Eligible Age

60 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Tufts University

OTHER

Sponsor Role lead

Responsible Party

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Jean Mayer USDA-Human Nutrition Research Center on Aging at Tufts University

Principal Investigators

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Kyung-Jin Yeum, Ph.D.

Role: PRINCIPAL_INVESTIGATOR

Tufts Medical Center

Locations

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Jean Mayer USDA-Human Nutrition Research Center on Aging at Tufts University

Boston, Massachusetts, United States

Site Status

Countries

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United States

Other Identifiers

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BioGreen 20070301034009

Identifier Type: -

Identifier Source: secondary_id

HNRCA2580

Identifier Type: -

Identifier Source: org_study_id

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