Vitamin D and Type 2 Diabetes - a Cross Sectional Study

NCT ID: NCT00695474

Last Updated: 2009-07-14

Basic Information

• Recruitment Status: COMPLETED
• Total Enrollment: 150 participants
• Study Classification: OBSERVATIONAL
• Study Start Date: 2008-06-30
• Study Completion Date: 2009-04-30

Brief Summary

The purpose of the study is to describe vitamin D status among patients with type 2 diabetes and to determine the association between serum 25-hydroxyvitamin D and glycemic control, markers of inflammation and blood pressure

Detailed Description

It has been estimated that 1 billion people worldwide have vitamin D deficiency or insufficiency. It is well known that vitamin D deficiency causes osteoporosis, increases the risk of fracture and causes muscle weakness. But there is now evidence that calcium malnutrition and hypovitaminosis D are predisposing conditions for various common chronic diseases such as malignancies (particularly colon, breast and prostate) chronic inflammatory and autoimmune disease (inflammatory bowel disease, multiple sclerosis) as well as metabolic disorders (metabolic syndrome, hypertension).

It has also been reported that vitamin D deficiency may predispose to glucose intolerance, altered insulin secretion and type 2 diabetes mellitus.

The purpose of this study is to determine vitamin D status among type 2 diabetics in our outpatient clinic and examine the relationship between vitamin D status , calcium and phosphorous metabolism, inflammatory markers, glycemic control, blood pressure and lipid profile.

Moreover the patients are asked to answer a questionnaire regarding lifestyle, exercise, sun exposure and food intake.

Conditions

Hypovitaminosis D; Type 2 Diabetes Mellitus

Study Design

• Observational Model Type: COHORT
• Study Time Perspective: CROSS_SECTIONAL

Study Groups

A

The cohort consists of type 2 diabetics from the outpatient clinic at Silkeborg Hospital.

No interventions assigned to this group

Eligibility Criteria

Inclusion Criteria

• Type 2 diabetes mellitus
• Patients of Danish extraction
• Written consent

Exclusion Criteria

• Renal failure (Urea > 12 mmol/l)
• Age < 18 years
• malabsorption

• Minimum Eligible Age: 18 Years
• Maximum Eligible Age: 90 Years
• Eligible Sex: ALL
• Accepts Healthy Volunteers: No

Sponsors

Aarhus University Hospital

OTHER

Sponsor Role: collaborator

Regionshospitalet Silkeborg

OTHER

Sponsor Role: collaborator

University of Aarhus

OTHER

Sponsor Role: lead

Responsible Party

Medical Department, Silkeborg Hospital

Principal Investigators

Lotte Oeskov, MD

Role: PRINCIPAL_INVESTIGATOR

Medical Department, Silkeborg Hospital, Falkevej 1-3, 8600 Silkeborg, Denmark

Other Identifiers

M-20080061

Identifier Type: -

Identifier Source: org_study_id