Guided Imagery for Military Sexual Trauma-Related Posttraumatic Stress Disorder (PTSD)

NCT ID: NCT00635635

Last Updated: 2010-05-26

Basic Information

• Recruitment Status: COMPLETED
• Clinical Phase: NA
• Total Enrollment: 40 participants
• Study Classification: INTERVENTIONAL
• Study Start Date: 2007-10-31
• Study Completion Date: 2010-05-31

Brief Summary

Military sexual trauma (MST) is a significant women's mental health issue. There is a crucial need for effective therapies for MST-related posttraumatic stress disorder (PTSD) that are well-tolerated and can be flexibly administered in a variety of treatment settings. Guided imagery is a novel, transportable intervention technique that meets these requirements and warrants research in PTSD. The proposed study will be a randomized controlled trial of the Guided Imagery for Trauma (GIFT) intervention for women veterans with MST-related PTSD. This minimal contact intervention is designed to increase coping, affect management and relaxation skills, and to fostering more positive images and beliefs associated with surviving trauma. The feasibility and tolerability of GIFT have already been demonstrated in an open-label pilot of 15 women veterans with MST-related PTSD, with very promising initial results.

Detailed Description

Study Aims: The primary aims of this study are: (1) To determine the efficacy of the GIFT intervention for women veterans with MST-related PTSD. (2) To determine the effects of GIFT on mental health and health services utilization, and neurobiological outcomes. (3) To identify predictors of GIFT treatment outcomes.

Research Plan: We will conduct a 12-week randomized, controlled trial of GIFT in 38 women veterans with MST-related PTSD. Half will be randomly assigned to GIFT and half to a music control group. GIFT includes a pretreatment orientation and midpoint consultation session with a clinician facilitator, a guided imagery audio, daily self-monitoring of audio use, and weekly telephone coaching calls with the facilitator. The music control condition is designed to control for all nonspecific aspects of GIFT and matches the GIFT protocol in all ways but the two specific "ingredients" through which GIFT is hypothesized to have its effect: (1) the guided imagery audio, and (2) the facilitator's help in structuring and focusing use of the guided imagery audio. Thus, the key differences between the two groups are that controls will receive an audio of the relaxing background music used on the guided imagery audio, but not the guided imagery exercises, and controls' contacts with the facilitator is limited to psychoeducational information and general support, and will not include help in structuring and focusing use of the audio, which is a key component of GIFT.

Conditions

Stress Disorder, Post Traumatic; Military Sexual Trauma

Study Design

• Allocation Method: RANDOMIZED
• Intervention Model: PARALLEL
• Primary Study Purpose: HEALTH_SERVICES_RESEARCH
• Blinding Strategy: TRIPLE

Study Groups

1

Guided Imagery Audio

Group Type: ACTIVE_COMPARATOR

Guided Imagery Audio

Intervention Type: BEHAVIORAL

Guided Imagery Audio listened to 5x per week

2

Music Audio

Group Type: ACTIVE_COMPARATOR

Music Audio

Intervention Type: BEHAVIORAL

Music only audio to be listened to 5x per week

Interventions

Guided Imagery Audio

Guided Imagery Audio listened to 5x per week

Intervention Type: BEHAVIORAL

Music Audio

Music only audio to be listened to 5x per week

Intervention Type: BEHAVIORAL

Eligibility Criteria

Inclusion Criteria

1. Age 18-65

2. Status as a women veteran

3. Receives care at the Durham VAMC

4. History of MST, confirmed by CAPS interview

5. DSM-IV diagnosis of PTSD, confirmed by CAPS interview

6. Able to participate in a research interview in English.

7. Regular telephone access

Exclusion Criteria

1. Current diagnosis of organic, psychotic, or bipolar disorder

2. Suicidality or parasuicidality

3. Ongoing family violence

4. Alcohol or drug abuse within previous 3 months

5. Enrolled in cognitive-behavioral/exposure-based therapy for PTSD during study period. Supportive therapy and some psychiatric medications (if stabilized at least 3 months prior to enrollment) are acceptable. Although patients may use medications, no new medications will be started during the study. This includes, but is not restricted to, SSRIs, benzodiazepines, barbiturates, antiepileptic drugs, antidepressants, buspirone, non-benzodiazepine hypnotics, stimulants, or antipsychotics.

• Minimum Eligible Age: 18 Years
• Maximum Eligible Age: 65 Years
• Eligible Sex: FEMALE
• Accepts Healthy Volunteers: No

Sponsors

National Institutes of Health (NIH)

NIH

Sponsor Role: collaborator

Durham VA Medical Center

FED

Sponsor Role: collaborator

Duke University

OTHER

Sponsor Role: lead

Responsible Party

Duke University Medical Center

Principal Investigators

Jennifer L Strauss, PhD

Role: PRINCIPAL_INVESTIGATOR

Duke University

Locations

Durham VA Medical Center

Durham, North Carolina, United States

Countries

United States

Other Identifiers

Pro00001282

Identifier Type: -

Identifier Source: org_study_id