Transcranial Magnetic Stimulation in Veterans With PTSD
NCT ID: NCT07336251
Last Updated: 2026-01-21
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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RECRUITING
NA
20 participants
INTERVENTIONAL
2026-01-15
2027-01-31
Brief Summary
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Detailed Description
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Conditions
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Study Design
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NA
SINGLE_GROUP
TREATMENT
NONE
Study Groups
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Participants receiving open label trial of TMS
Transcranial Magnetic Stimulation
10 sessions of low frequency rTMS (1Hz) applied to the right dorsolateral prefrontal cortex.
Interventions
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Transcranial Magnetic Stimulation
10 sessions of low frequency rTMS (1Hz) applied to the right dorsolateral prefrontal cortex.
Eligibility Criteria
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Inclusion Criteria
* Eligible for VA healthcare
* Moderate to severe PTSD as determined by a total score of at least 25 on the CAPS within 7 days of randomization.
* Agree to have CAPS audio recorded.
* Ability to obtain a Motor Threshold using the TMS device during screening.
* If female with childbearing potential, use of acceptable method of birth control (i.e., use of contraceptives, abstinence).
* Able to read, understand, and sign the informed consent document.
Exclusion Criteria
* MRI is contraindicated
* Current use of clozapine (any dose) or bupropion (more than 300mg per day).
* Cardiac pacemaker or implantable defibrillator.
* Presence of any metal object in the head, including cochlear implants, but excluding dental work in the mouth.
* Significant central nervous system disorder (stroke, brain mass, epilepsy).
* Seizure in past one year.
* Current psychosis or mania.
* Significant suicidal ideation.
* Unstable medical conditions.
* Current alcohol or substance use disorder (except nicotine) that interferes with the patient's ability to participate.
* CPT or PE for PTSD in the past 2 months.
* Changes in Fluoxetine, Paroxetine, Sertraline, or Venlafaxine in the past 2 months.
* Color blind
* Currently participating in other research studies.
* Aneurysm Clip
* Ocular foreign body (e.g., metal shavings)
* Any implanted device (pumps, infusion devices, etc.)
* Shrapnel injuries or metal fragments
19 Years
70 Years
ALL
No
Sponsors
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White River Junction Veterans Affairs Medical Center
FED
Responsible Party
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Bradley Watts
Staff Psychiatrist
Principal Investigators
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Bradley Watts
Role: PRINCIPAL_INVESTIGATOR
US Department of Veterans Affairs
Locations
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White River Junction VA Hospital
White River Junction, Vermont, United States
Countries
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Central Contacts
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Facility Contacts
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Other Identifiers
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1869595
Identifier Type: -
Identifier Source: org_study_id
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