A Methodology Study Of Brain Imaging Of Pain-Killers In Post-Traumatic Neuropathic Pain Patients
NCT ID: NCT00610155
Last Updated: 2021-01-22
Study Results
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View full resultsBasic Information
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COMPLETED
NA
18 participants
INTERVENTIONAL
2008-09-30
2010-07-31
Brief Summary
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Detailed Description
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Conditions
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Study Design
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RANDOMIZED
CROSSOVER
TREATMENT
TRIPLE
Study Groups
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1
Placebo
BID
2
Pregabalin
Dose 75 mg titrated to 150 mg, bid
3
Tramadol SR
Dose 50mg titrated to 200 mg, bid
Interventions
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Placebo
BID
Pregabalin
Dose 75 mg titrated to 150 mg, bid
Tramadol SR
Dose 50mg titrated to 200 mg, bid
Eligibility Criteria
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Inclusion Criteria
* Brush allodynia score of ≥4 and calculated average pain score of ≥3 on an 11-point numerical rating scale by the completion of down-titration of existing medications.
* Right-handed
Exclusion Criteria
* Phantom limb pain, painful diabetic neuropathy.
* Subjects with any other co-existing pain which he/she or a qualified pain physician cannot differentiate from NeP of peripheral origin.
* Subjects with diabetes mellitus and with an HbA1C value of \>10% upon measurement at screening.
18 Years
75 Years
ALL
No
Sponsors
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University of Oxford
OTHER
Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
INDUSTRY
Responsible Party
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Principal Investigators
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Pfizer CT.gov Call Center
Role: STUDY_DIRECTOR
Pfizer
Locations
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Pfizer Investigational Site
Portsmouth, Hampshire, United Kingdom
Pfizer Investigational Site
Solihull, West Midlands, United Kingdom
Countries
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Other Identifiers
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A0081173
Identifier Type: -
Identifier Source: org_study_id
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