Confocal Reflectance Microscopy of Shave-Biopsy Sites on Skin in Vivo.

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

COMPLETED

Total Enrollment

116 participants

Study Classification

OBSERVATIONAL

Study Start Date

2006-02-14

Study Completion Date

2018-02-23

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

The purpose of this study is to evaluate a new instrument that shines light and takes digital pictures of skin. The goal is to develop a technique that may enable fast and accurate detection of skin disorders and cancers for future clinical diagnosis and surgical use.

Related Clinical Trials

Explore similar clinical trials based on study characteristics and research focus.

Confocal Microscopy of Benign and Malignant Skin Tumors

NCT01010321

Skin Cancer

SUSPENDED

Reflectance Confocal Microscopy in Basal Cell Carcinoma

NCT02623101

Carcinoma, Basal Cell

COMPLETED NA

Multi-Wavelength and Coherence Confocal Reflectance Microscopy of Pigmented and Non-Pigmented Lesions on the Skin In-Vivo

NCT00574392

Basal Cell Carcinoma Melanoma Non-Malignant Skin Disorders +1 more

COMPLETED

One-stop-shop Study for Treatment of Basal Cell Carcinoma Using Reflectance Confocal Microscopy

NCT02285790

Carcinoma, Basal Cell

COMPLETED NA

Intravital Microscopy for Identifying Tumor Vessels in Patients With Stage IA-IV Melanoma That is Being Removed by Surgery

NCT01886235

Recurrent Melanoma Stage IA Skin Melanoma Stage IB Skin Melanoma +7 more

COMPLETED NA

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Basal Cell Carcinoma Melanoma Squamous Cell Carcinoma Non-Malignant Skin Disorders

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

Review each arm or cohort in the study, along with the interventions and objectives associated with them.

1

Patients undergoing a shave biopsy and confocal microscopy.

confocal microscopy in vivo

Intervention Type PROCEDURE

A dermatologist will perform a shave biopsy according to standard clinical procedures. This study will be carried out after the shave biopsy. The deep surface and the peripheral margins will be imaged on each patient.

Interventions

Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.

confocal microscopy in vivo

A dermatologist will perform a shave biopsy according to standard clinical procedures. This study will be carried out after the shave biopsy. The deep surface and the peripheral margins will be imaged on each patient.

Intervention Type PROCEDURE

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

* Patients undergoing shave-biopsy on an anatomical site that is readily accessible to the VivaScope 1500 (for example, chest, back, legs, arms, cheek, forehead).
* The additional 110 patients for this amendment will be imaged with the newly developed Vivascope 3000 handheld confocal microscope.
* Ability to sign informed consent.
* Age ≥ 18 years.

Exclusion Criteria

* Shave-biopsy located on a site that is not amenable to confocal imaging (for example, adjacent to the nose, ears or eyes, fingers, toes).
* Inability to give informed consent.
* Known hypersensitivity to adhesive rings.
* Inability to tolerate imaging procedure (i. e., remain relatively still for multiple short durations of 3-4 minutes).

Minimum Eligible Age

18 Years

Maximum Eligible Age

80 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No