Using High Resolution Function Imaging To Detect Melanoma and Dysplastic Nevi

NCT ID: NCT01118832

Last Updated: 2019-02-08

Basic Information

• Recruitment Status: COMPLETED
• Total Enrollment: 30 participants
• Study Classification: OBSERVATIONAL
• Study Start Date: 2009-09-22
• Study Completion Date: 2012-02-20

Brief Summary

A novel infrared imaging tool to aid in the clinical detection of atypical pigmented lesions and melanoma is developed. Goals include evaluation of the utility of high-resolution infrared scanning of cutaneous lesions in the diagnosis of pigmented lesions and the identification of high-risk lesions and melanomas.

Detailed Description

This study uses a specific skin protocol to cool the skin and then measures the cutaneous thermal recovery to uniquely identify lesions that may be cancerous. Using computer models, the thermal signature is used to determine the size and shape of the lesions in question. In particular, this study seeks to add quantification analysis of high resolution thermal images of melanoma lesions to provide accurate early diagnostic capability with specific detail regarding size, shape and depth of the lesions. This information will be compared to biopsy results and surgical resection results.

Conditions

Melanoma

Study Design

• Observational Model Type: CASE_ONLY
• Study Time Perspective: OTHER

Eligibility Criteria

Inclusion Criteria

• Patients seen in the high-risk pigmented lesion clinic, who posses a pigmented lesion with a clinical indication for biopsy

Exclusion Criteria

• None

• Minimum Eligible Age: 10 Years
• Maximum Eligible Age: 80 Years
• Eligible Sex: ALL
• Accepts Healthy Volunteers: Yes

Sponsors

Johns Hopkins University

OTHER

Sponsor Role: collaborator

National Cancer Institute (NCI)

NIH

Sponsor Role: collaborator

Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins

OTHER

Sponsor Role: lead

Responsible Party

Responsibility Role: SPONSOR

Principal Investigators

Cila Herman, Dr-Ing.

Role: PRINCIPAL_INVESTIGATOR

Johns Hopkins University

Locations

Johns Hopkins Medicine

Baltimore, Maryland, United States

Countries

United States

References

C HERMAN, THREE-DIMENSIONAL THERMAL IMAGING FOR THE DETECTION OF SKIN LESIONS AND OTHER NATURAL AND ABNORMAL CONDITIONS - WO Patent WO/2012/009,359, 2012

Reference Type: BACKGROUND

Herman C. Emerging technologies for the detection of melanoma: achieving better outcomes. Clin Cosmet Investig Dermatol. 2012;5:195-212. doi: 10.2147/CCID.S27902. Epub 2012 Nov 12.

Reference Type: RESULT

PMID: 23204850 (View on PubMed)

Related Links

http://www.jove.com/video/2679/quantitative-visualization-detection-skin-cancer-using-dynamic

Video article describing the melanoma scanner

http://www.dovepress.com/emerging-technologies-for-the-detection-of-melanoma-achieving-better-o-peer-reviewed-article-CCID

Review article discussing emerging technologies for the detection of melanoma

http://releases.jhu.edu/2010/02/26/scanning-for-skin-cancer-infrared-system-looks-for-deadly-melanoma/

Johns Hopkins News release about the infrared scanner for detection of skin cancer

Other Identifiers

R01CA161265-02

Identifier Type: NIH

Identifier Source: secondary_id

View Link

NA_00016040

Identifier Type: OTHER

Identifier Source: secondary_id

J0868

Identifier Type: -

Identifier Source: org_study_id