Chlamydia Trachomatis Persistence in the Female Gastrointestinal Tract

NCT ID: NCT00578188

Last Updated: 2016-04-13

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

WITHDRAWN

Study Classification

OBSERVATIONAL

Study Start Date

2006-02-28

Study Completion Date

2008-01-31

Brief Summary

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The purpose of this study is to determine if Chlamydial infections persist in the rectum of females who have had a sexually transmitted infection of Chlamydia.

Detailed Description

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Conditions

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Chlamydia Infection

Study Design

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Observational Model Type

CASE_CONTROL

Study Time Perspective

PROSPECTIVE

Study Groups

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RP100-400

Subjects with Chlamydia. The control group will also be identified with these numbers.

No interventions assigned to this group

Eligibility Criteria

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Inclusion Criteria

* 11-19 years old
* Female
* Diagnosis of Chlamydia on enrollment visit
* Invitation to participate control group

Exclusion Criteria

* Age out of range
* Negative Chlamydia screen (unless qualifies for control group)
* Unable to provide needed samples
Minimum Eligible Age

11 Years

Maximum Eligible Age

19 Years

Eligible Sex

FEMALE

Accepts Healthy Volunteers

Yes

Sponsors

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Arkansas Children's Hospital Research Institute

OTHER

Sponsor Role lead

Responsible Party

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Arkansas Children's Hospital Research Institute

Principal Investigators

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Amy M Scurlock, MD

Role: PRINCIPAL_INVESTIGATOR

Arkansas Children's Hospital Research Institute

Locations

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Arkansas Children's Hospital

Little Rock, Arkansas, United States

Site Status

Countries

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United States

References

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Centers for Disease Control and Prevention (CDC). Chlamydia trachomatis genital infections--United States, 1995. MMWR Morb Mortal Wkly Rep. 1997 Mar 7;46(9):193-8.

Reference Type BACKGROUND
PMID: 9072679 (View on PubMed)

Dean D, Suchland RJ, Stamm WE. Evidence for long-term cervical persistence of Chlamydia trachomatis by omp1 genotyping. J Infect Dis. 2000 Sep;182(3):909-16. doi: 10.1086/315778. Epub 2000 Aug 17.

Reference Type BACKGROUND
PMID: 10950788 (View on PubMed)

Jones RB, Rabinovitch RA, Katz BP, Batteiger BE, Quinn TS, Terho P, Lapworth MA. Chlamydia trachomatis in the pharynx and rectum of heterosexual patients at risk for genital infection. Ann Intern Med. 1985 Jun;102(6):757-62. doi: 10.7326/0003-4819-102-6-757.

Reference Type BACKGROUND
PMID: 3888022 (View on PubMed)

Cotter TW, Ramsey KH, Miranpuri GS, Poulsen CE, Byrne GI. Dissemination of Chlamydia trachomatis chronic genital tract infection in gamma interferon gene knockout mice. Infect Immun. 1997 Jun;65(6):2145-52. doi: 10.1128/iai.65.6.2145-2152.1997.

Reference Type BACKGROUND
PMID: 9169744 (View on PubMed)

Igietseme JU, Portis JL, Perry LL. Inflammation and clearance of Chlamydia trachomatis in enteric and nonenteric mucosae. Infect Immun. 2001 Mar;69(3):1832-40. doi: 10.1128/IAI.69.3.1832-1840.2001.

Reference Type BACKGROUND
PMID: 11179361 (View on PubMed)

Related Links

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http://www.archildrens.org

Arkansas Children's Hospital Main Page

Other Identifiers

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ACH GL #039005

Identifier Type: -

Identifier Source: secondary_id

IRB # 43921

Identifier Type: -

Identifier Source: org_study_id

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