Functional Organization of Somatosensory Responses in the Secondary Somatosensitive Area and Insula
NCT ID: NCT00542906
Last Updated: 2009-06-17
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
NA
25 participants
INTERVENTIONAL
2007-10-31
2008-04-30
Brief Summary
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The aim of this fMRI study is to determine the functional cartography of SII and insula. The localization of responses to different somatosensory stimuli (slight touch, warm, cold, heat pain and arthrokinesia) applied on the left hand of 25 healthy volunteers, will be compared.
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Detailed Description
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Conditions
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Study Design
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NA
SINGLE_GROUP
TREATMENT
NONE
Study Groups
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1
healthy volunteers
localization
localization of the several types of somatosensory stimuli
Interventions
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localization
localization of the several types of somatosensory stimuli
Eligibility Criteria
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Inclusion Criteria
* contraception needed for women
* right handed
* All the subjects have to give their written informed consent.
Exclusion Criteria
* neurological or psychiatric disease
* drugs taken \<12h before fMRI
* contra-indications to fMRI : pacemaker, clip, metallic device
* Refusing to be informed of the presence of a cerebral abnormality, detected during MRI.
18 Years
50 Years
ALL
Yes
Sponsors
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Centre Hospitalier Universitaire de Saint Etienne
OTHER
Responsible Party
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Centre Hospitalier Universitaire de Saint Etienne
Principal Investigators
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Laure Mazzola, MD
Role: PRINCIPAL_INVESTIGATOR
CHU de Saint-Etienne
Locations
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Service de Neurologie - CHU de Saint-Etienne
Saint-Etienne, , France
Countries
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References
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Mazzola L, Isnard J, Mauguiere F. Somatosensory and pain responses to stimulation of the second somatosensory area (SII) in humans. A comparison with SI and insular responses. Cereb Cortex. 2006 Jul;16(7):960-8. doi: 10.1093/cercor/bhj038. Epub 2005 Sep 21.
Peyron R, Schneider F, Faillenot I, Convers P, Barral FG, Garcia-Larrea L, Laurent B. An fMRI study of cortical representation of mechanical allodynia in patients with neuropathic pain. Neurology. 2004 Nov 23;63(10):1838-46. doi: 10.1212/01.wnl.0000144177.61125.85.
Other Identifiers
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2007-A00328-45
Identifier Type: -
Identifier Source: secondary_id
DGS 2007-0273
Identifier Type: -
Identifier Source: secondary_id
0701023
Identifier Type: -
Identifier Source: org_study_id
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