Language in Primary Progressive Aphasia

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Total Enrollment

500 participants

Study Classification

OBSERVATIONAL

Study Start Date

2007-05-31

Study Completion Date

2027-04-30

Brief Summary

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The purpose of this study is to further define the neurological and linguistic deterioration in primary progressive aphasia.

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Detailed Description

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The Language in Primary Progressive Aphasia (PPA) aims to understand the behavioral, anatomical and physiological changes in people with PPA throughout the course of the illness. The researchers in this study want to increase awareness of PPA, educate others about this unique disorder, and to encourage more research to eventually develop therapies.

During the three-day research program, participants will be asked to undergo neuropsychological testing (paper and pencil tests that evaluate cognition), advanced imaging (MRI and PET), cognitive experiments, and other computer and language testing batteries. Participants may be asked to return every two years to complete the same measures.

For participants not living near Chicago, IL, flights and accommodations (for both the person with PPA and their companion) will be covered by the study.

Conditions

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Primary Progressive Aphasia

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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PPA (Primary Progressive Aphasia)

Individuals with primary progressive aphasia

No interventions assigned to this group

Control

Individuals with no diagnosis of any type of dementia

No interventions assigned to this group

Eligibility Criteria

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Inclusion Criteria

* Diagnosis of primary progressive aphasia
* Right-handed
* Native English speaker
* Visual acuity of 20/30 corrected
* Adequate hearing to follow conversation
* Safe for an MRI scan

Exclusion Criteria

* Left-handedness
* Claustrophobia
* Presence of significant medical illness that initially or in the future could interfere with continued participation in the study

Eligible Sex

ALL

Accepts Healthy Volunteers

No