Hemodynamic Parameters in Euthyroid Patients With Thyroid Nodules

NCT ID: NCT00507897

Last Updated: 2008-02-07

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

TERMINATED

Total Enrollment

100 participants

Study Classification

OBSERVATIONAL

Study Completion Date

2007-12-31

Brief Summary

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The purpose of this study is to determine the relationship of hemodynamic parameters with the level of thyroid hormones and the histological structure of thyroid nodules in euthyroid patients.

Detailed Description

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As opposed to widely investigated condition of cardiovascular system in patients with functional disorders of thyroid gland, the relationship between thyroid hormones and hemodynamic parameters in euthyroid patients remains not enough clear.

We detect the parameters of blood pressure and thyroid hormones in euthyroid patients with thyroid nodules directly before planned operation on the thyroid gland.

As the study is carries out directly before operation, that assumes presence of preoperative stress in patients, activity of the sympatho - adrenal system is estimated in addition.

On the one hand, the design of our research will allow to estimate relationship of thyroid hormones with the parameters of blood pressure in conditions of euthyroidism, on the other hand - to investigate features of blood pressure in patients with thyroid nodules.

The research of the patients in the preoperative period will enable to select the group of patients without pathology of cardiovascular system whose increased blood pressure is connected with preoperative stress, that in turn will allow to exclude influence of the pathology of the cardiovascular system on studied correlation.

Conditions

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Thyroid Nodules

Study Design

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Study Time Perspective

PROSPECTIVE

Study Groups

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A

Cohort: Patients with normal blood pressure scheduled to have thyroid nodules surgically removed

No interventions assigned to this group

A1

Patients from group A not receiving any drugs and who lack other pathology, gender and age matched group B1

No interventions assigned to this group

B

Cohort: Patients with increased blood pressure scheduled to have thyroid nodules surgically removed

No interventions assigned to this group

B1

Patients from group B not receiving any drugs and who lack other pathology, gender and age matched group A1

No interventions assigned to this group

Eligibility Criteria

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Inclusion Criteria

* Euthyroid patients with thyroid nodules before operation on the thyroid gland

Exclusion Criteria

* Hyperthyroidism
* Hypothyroidism
Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Yaroslavl State Medical Academy

OTHER

Sponsor Role lead

Principal Investigators

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Yuriy Alexandrov, Professor

Role: STUDY_CHAIR

Yaroslavl State Medical Academy

Locations

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Yaroslavl State Medical Academy

Yaroslavl, , Russia

Site Status

Countries

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Russia

Other Identifiers

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ESheverdova-1

Identifier Type: -

Identifier Source: org_study_id

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