Color Flow Doppler Ultrasound in Subclinical Thyroid Dysfunction

NCT ID: NCT00437931

Last Updated: 2016-09-08

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

60 participants

Study Classification

OBSERVATIONAL

Study Start Date

2007-02-28

Study Completion Date

2008-02-29

Brief Summary

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Overt hyperthyroidism and hypothyroidism are associated with inverted hemodynamic changes.Regional blood flow disturbances (including intrathyroidal) were also reported in these thyroid disorders. The purpose of this study is to investigate the thyroid vascularity and blood flow by Color Flow Doppler Sonography in patients with subclinical thyroid dysfunction

Detailed Description

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Color Flow Doppler Sonography (CFDS) has become in the last years an increasing procedure to assess the thyroid blood flow. Previous studies showed specific changes of thyroid blood flow in hyperthyroidism, Hashimoto's thyroiditis and thyroid nodules when investigated by CFDS. Subclinical hyperthyroidism and hypothyroidism are common laboratory findings, defined by normal thyroid hormones concentrations along with ,respectively,decreased or increase Thyroid stimulating hormone (TSH) level. We purpose to investigate thyroid vascularity by CFDS in patients with subclinical hyperthyroidism or hypothyroidism and compared them with euthyroid patients.

Conditions

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Subclinical Hypothyroidism Hyperthyroidism Thyroid Dysfunction

Study Design

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Observational Model Type

CASE_CONTROL

Study Time Perspective

PROSPECTIVE

Study Groups

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A

patients with subclinical hypothyroidism

No interventions assigned to this group

B

patients with subclinical hyperthyroidism

No interventions assigned to this group

C

patient with normal thyroid function.

No interventions assigned to this group

Eligibility Criteria

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Inclusion Criteria

* patients with subclinical hypothyroidism or hyperthyroidism
* patients with thyroid nodules and normal thyroid function

Exclusion Criteria

* patients who are taking thyroxine, antithyroid drugs, lithium or amiodarone
* patients who had thyroid surgery or radioiodine therapy
* patients with NYHA class 3 or 4 heart failure
Minimum Eligible Age

18 Years

Maximum Eligible Age

75 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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HaEmek Medical Center, Israel

OTHER

Sponsor Role lead

Responsible Party

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avraham ishay

Dr

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Avraham Ishay, MD

Role: PRINCIPAL_INVESTIGATOR

Haemek Medical Center, Endocrine Institute, Afula, Israel

Leonid Chervinsky

Role: STUDY_CHAIR

Haemek Medical Center, Department of Radiology, Afula , Israel

Rafael Luboshitzky, MD

Role: STUDY_CHAIR

Haemek Medical Center, Endocrine Institute, Afula, Israel

Locations

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Haemek Medical Center, Department of Radiology

Afula, , Israel

Site Status

Countries

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Israel

Other Identifiers

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006-07-EMC

Identifier Type: -

Identifier Source: org_study_id

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