Additional Glucose Lowering and Anti-Inflammatory Effects by Acarbose and Alcohol in Subjects With Impaired Glucose Tolerance or Mild Type 2 Diabetes

NCT ID: NCT00417950

Last Updated: 2007-01-04

Basic Information

• Recruitment Status: UNKNOWN
• Clinical Phase: NA
• Total Enrollment: 30 participants
• Study Classification: INTERVENTIONAL
• Study Start Date: 2007-01-31

Brief Summary

To understand if acarbose, an alpha-glucosidase inhibitor usually for treating diabetes, will further lower post meal glucose and inflammatory state when taking together with moderate amount of alcohol during meal tolerance test in subjects with impaired glucose tolerance or mild diabetes.

Conditions

Diabetes Mellitus; Impaired Glucose Tolerance

Study Design

• Allocation Method: RANDOMIZED
• Intervention Model: SINGLE_GROUP
• Primary Study Purpose: TREATMENT
• Blinding Strategy: NONE

Interventions

Acarbose

Intervention Type: DRUG

Eligibility Criteria

Inclusion Criteria

• Subjects with mild diabetes without prior medications or impaired glucose tolerance

Exclusion Criteria

• Pregnancy
• Recent major cardiac, renal and hepatic disease
• Intolerance to alcohol
• Allergy to acarbose treatment

• Minimum Eligible Age: 25 Years
• Maximum Eligible Age: 75 Years
• Eligible Sex: ALL
• Accepts Healthy Volunteers: No

Sponsors

Tri-Service General Hospital

OTHER

Sponsor Role: collaborator

Taichung Veterans General Hospital

OTHER

Sponsor Role: lead

Principal Investigators

Wayne H Sheu, MD, PhD

Role: PRINCIPAL_INVESTIGATOR

Taichung Veterans General Hospital

Locations

Taichung Veterans General Hospital

Taichung, , Taiwan

Site Status: RECRUITING

Countries

Taiwan

Central Contacts

I Te Lee, MD, MS

Role: CONTACT

itlee@vghtc.gov.tw

886-4-23592525 ext. 3065

Facility Contacts

Wayne H Sheu, MD, PhD

Role: primary

whhsheu@vghtc.gov.tw

886-4-23592525 ext. 3068

Other Identifiers

950801/C06138

Identifier Type: -

Identifier Source: org_study_id