Effects of Peritendinous Corticosteroid Injections, Eccentric Training and Heavy Slow Resistance Training in Patellar Tendinopathy

NCT ID: NCT00404469

Last Updated: 2008-05-22

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

39 participants

Study Classification

INTERVENTIONAL

Study Start Date

2006-03-31

Study Completion Date

2007-11-30

Brief Summary

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We will investigate the effect of peritendinous corticosteroid injections, eccentric training and heavy resistance training in male patellar tendinopathy patients. The purpose is to compare the clinical effect of these three treatments in a randomised controlled trial. Also we wish to investigate the treatment mechanisms responsible for the effectiveness of the three treatments.

Detailed Description

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3 interventions groups as described above (n=13 in each group) 12 weeks intervention period. Clinical assessments before and after intervention: VAS, VISA, Tendon thickness, Doppler us activity.

Before and after intervention tendon biopsies will be taken and analyzed for crosslinks and fibril diameter. Also tendon mechanical properties will be measured. Tendon and muscle structural properties will be measured with MRI.

Treatment satisfaction will be stated after intervention period.

Conditions

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Patellar Tendinopathy / Jumpers Knee

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

BASIC_SCIENCE

Blinding Strategy

SINGLE

Investigators

Study Groups

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CORT

Peritendinous corticosteroid injections at 0 and 4 weeks. 12 weeks total

Group Type ACTIVE_COMPARATOR

peritendinous corticosteroid injections

Intervention Type PROCEDURE

1 ml of40mg/ml methylprednisolone acetate at 0 and 4 weeks. 2 week observational

ECC

12 weeks of eccentric unilateral decline squats

Group Type EXPERIMENTAL

eccentric decline squat training

Intervention Type PROCEDURE

eccentric decline unilateral squats performed twice daily. for 12 weeks

HSR

Heavy slow resistance training. 3/week. 12 weeks

Group Type EXPERIMENTAL

heavy slow resistance training

Intervention Type PROCEDURE

Heavy slow resistance training for knee extensors. 3/week. total of 12 weeks

Interventions

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peritendinous corticosteroid injections

1 ml of40mg/ml methylprednisolone acetate at 0 and 4 weeks. 2 week observational

Intervention Type PROCEDURE

eccentric decline squat training

eccentric decline unilateral squats performed twice daily. for 12 weeks

Intervention Type PROCEDURE

heavy slow resistance training

Heavy slow resistance training for knee extensors. 3/week. total of 12 weeks

Intervention Type PROCEDURE

Eligibility Criteria

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Inclusion Criteria

* Clinical patellar tendinopathy pain.
* Tendon swelling
* Hypoechoic
* Doppler activity in tendon

Exclusion Criteria

* Previous knee surgery
* diabetes
* arthritis
* previous steroid injections
Minimum Eligible Age

18 Years

Maximum Eligible Age

55 Years

Eligible Sex

MALE

Accepts Healthy Volunteers

No

Sponsors

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Bispebjerg Hospital

OTHER

Sponsor Role lead

Principal Investigators

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Mads Kongsgaard, PhD., MSc.

Role: PRINCIPAL_INVESTIGATOR

Institute of Sports Medicine, Copenhagen

Locations

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Institute of Sports Medicine Copenhagen. Dept 8 1st floor. Bispebjerg Hospital

Copenhagen, , Denmark

Site Status

Countries

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Denmark

Other Identifiers

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Patellar tendinopathy

Identifier Type: -

Identifier Source: org_study_id