A Study of the Effect of Time-of-day of Training on Chronic Patellar Tendinopathy
NCT ID: NCT06217432
Last Updated: 2024-01-22
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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RECRUITING
NA
70 participants
INTERVENTIONAL
2024-01-10
2025-12-31
Brief Summary
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Detailed Description
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Conditions
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Study Design
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RANDOMIZED
PARALLEL
BASIC_SCIENCE
DOUBLE
Study Groups
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Morning exercise
Three sessions per week of targeted resistance exercise targeting the quadriceps muscles performed between 6:00 and 8:00 for 12 weeks.
Resistance training for knee extensors
The exercise will be started at 60% of 1 repetition maximum (RM) and progressed to 75% of 1 RM during the first 3 weeks and maintained throughout the intervention period. The exercise will be performed slowly (6 s/ repetition).
Late afternoon exercise
Three sessions per week of targeted resistance exercise targeting the quadriceps muscles performed between 16:00 and 18:00 for 12 weeks.
Resistance training for knee extensors
The exercise will be started at 60% of 1 repetition maximum (RM) and progressed to 75% of 1 RM during the first 3 weeks and maintained throughout the intervention period. The exercise will be performed slowly (6 s/ repetition).
Healthy control
Healthy individuals without tendinopathy as controls for the transcriptomics and proteomics analyses.
No interventions assigned to this group
Interventions
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Resistance training for knee extensors
The exercise will be started at 60% of 1 repetition maximum (RM) and progressed to 75% of 1 RM during the first 3 weeks and maintained throughout the intervention period. The exercise will be performed slowly (6 s/ repetition).
Eligibility Criteria
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Inclusion Criteria
* Age (18-55) years old
* BMI (18.5-30)
* Uni- or bilateral patellar tendinopathy
* Symptom onset \>90 days ago
Exclusion Criteria
* Previous surgery in the knee on the ipsilateral side
* Corticosteroid injection in the patellar tendon on the ipsilateral side within the last 6 months
* Any confounding diagnosis to the knee joint
* Known arthritis
* Known diabetes
* Known rheumatic disorders
* Inability to follow rehabilitation or complete follow-ups
* Enrolled in a resistance based-rehabilitation program for the affected patellar tendon within the previous 3 months
* Have an occupation where it is not feasible to avoid pain provoking tasks
* Pregnancy
* Have sleeping disorders or disruptions, e.g., night shift work
* Use of medicines or supplements known to affect collagen synthesis or sleep
18 Years
55 Years
ALL
Yes
Sponsors
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Bispebjerg Hospital
OTHER
Responsible Party
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Chloé Yeung
Senior Researcher
Locations
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Institute of Sports Medicine Copenhagen
Copenhagen NV, Capital Region, Denmark
Countries
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Central Contacts
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Facility Contacts
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Other Identifiers
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TENDOTIME
Identifier Type: -
Identifier Source: org_study_id
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