Split-Thickness Skin Graft Donor Site Wound Healing Study

NCT ID: NCT00392301

Last Updated: 2018-02-22

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

WITHDRAWN

Study Classification

OBSERVATIONAL

Study Start Date

2009-10-31

Study Completion Date

2012-07-01

Brief Summary

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The purpose of this research study is to discover whether instruments widely used in skin research can be used to measure wound healing in split thickness skin graft donor sites and whether these instruments can detect differences in healing when two different dressing products are used.

Detailed Description

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Currently there is no standard treatment to promote wound healing for split thickness skin graft donor sites and healing is determined based on clinical observation of the graft donor site and clinical judgement. Here we propose to use two instruments commonly used in skin research to measure wound healing. This study will validate the use of these two instruments, one that measures transepidermal water loss and the other that measures skin pigmentation to determine healing. To further validate the use of these instruments we will determine if these instruments can detect differences between two different wound dressing products that have been previously reported to heal skin graft donor sites at different rates.

Conditions

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Split-thickness Skin Graft Donor Sites

Study Design

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Observational Model Type

OTHER

Study Time Perspective

PROSPECTIVE

Eligibility Criteria

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Inclusion Criteria

* Participants 18 years of age and over who have a split-thickness skin graft donor site.

Exclusion Criteria

* Individuals under 18 years of age.
* Individuals who do not have a split thickness skin graft donor site.
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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University of Mississippi Medical Center

OTHER

Sponsor Role lead

Responsible Party

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Annette Wysocki, PhD, RN

Associate Dean for Research and Professor

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Annette B. Wysocki, PhD, RN

Role: PRINCIPAL_INVESTIGATOR

University of Mississippi Medical Center

Locations

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University of Mississippi Medical Center

Jackson, Mississippi, United States

Site Status

Countries

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United States

References

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Disa JJ, Alizadeh K, Smith JW, Hu Q, Cordeiro PG. Evaluation of a combined calcium sodium alginate and bio-occlusive membrane dressing in the management of split-thickness skin graft donor sites. Ann Plast Surg. 2001 Apr;46(4):405-8. doi: 10.1097/00000637-200104000-00009.

Reference Type BACKGROUND
PMID: 11324883 (View on PubMed)

Feldman DL, Rogers A, Karpinski RH. A prospective trial comparing Biobrane, Duoderm and xeroform for skin graft donor sites. Surg Gynecol Obstet. 1991 Jul;173(1):1-5.

Reference Type BACKGROUND
PMID: 1907769 (View on PubMed)

Feldman DL. Which dressing for split-thickness skin graft donor sites? Ann Plast Surg. 1991 Sep;27(3):288-91. doi: 10.1097/00000637-199109000-00017.

Reference Type BACKGROUND
PMID: 1952757 (View on PubMed)

Kilinc H, Sensoz O, Ozdemir R, Unlu RE, Baran C. Which dressing for split-thickness skin graft donor sites? Ann Plast Surg. 2001 Apr;46(4):409-14. doi: 10.1097/00000637-200104000-00010.

Reference Type BACKGROUND
PMID: 11324884 (View on PubMed)

Malpass KG, Snelling CF, Tron V. Comparison of donor-site healing under Xeroform and Jelonet dressings: unexpected findings. Plast Reconstr Surg. 2003 Aug;112(2):430-9. doi: 10.1097/01.PRS.0000070408.33700.C7.

Reference Type BACKGROUND
PMID: 12900600 (View on PubMed)

Rakel BA, Bermel MA, Abbott LI, Baumler SK, Burger MR, Dawson CJ, Heinle JA, Ocheltree IM. Split-thickness skin graft donor site care: a quantitative synthesis of the research. Appl Nurs Res. 1998 Nov;11(4):174-82. doi: 10.1016/s0897-1897(98)80296-6.

Reference Type BACKGROUND
PMID: 9852660 (View on PubMed)

Other Identifiers

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2006-0094

Identifier Type: -

Identifier Source: org_study_id

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