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Wound-healing Improvement by Resurfacing Split-Thickness Skin Donor Sites With Thin Split-thickness Grafting

NCT ID: NCT01974583

Last Updated: 2013-11-01

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

192 participants

Study Classification

OBSERVATIONAL

Study Start Date

2002-01-31

Study Completion Date

2013-03-31

Brief Summary

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Split-thickness skin grafting remains fundamental treatment of patients with deep burns and other traumatic injuries. However, the split-thickness skin graft (STSG) donor site dressing has been controversial until now. Our study here aimed to assess patient comfort and wound-healing efficacy with the application of thin split-thickness grafting on STSG donor sites.

Detailed Description

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Background：Split-thickness skin grafting remains fundamental treatment of patients with deep burns and other traumatic injuries. However, the split-thickness skin graft (STSG) donor site dressing has been controversial until now. Our study here aimed to assess patient comfort and wound-healing efficacy with the application of thin split-thickness grafting on STSG donor sites.

Methods: 192 consecutive patients undergoing split-thickness skin grafting were included in the study and the participants were randomly divided into three groups: Group A was regrafted with thin STSG, while, Group B and Group C were covered with the occlusive hydrocellular dressing and paraffin gauze, respectively. The three groups were compared regarding to the time of epithelialization, pain sensed by the patients and the scar formation.

Conditions

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Skin Graft Disorder Disorder of Skin Donor Site Wound Healing Disturbance of

Keywords

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the split-thickness skin graft （STSG） donor site regraft wound healing

Study Design

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Observational Model Type

CASE_CONTROL

Study Time Perspective

PROSPECTIVE

Study Groups

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the treatment group A

The people in treatment group were regrafted with thin split-thickness skin graft

regrafted with thin split-thickness skin graft

Intervention Type PROCEDURE

Group A (the treatment group) were regrafted with thin split-thickness skin graft

the control group B

The group B covered with the occlusive hydrocellular dressing (Allevyn Adhesive, Smith \& Nephew)

covered with the occlusive hydrocellular dressing

Intervention Type PROCEDURE

group B covered with the occlusive hydrocellular dressing (Allevyn Adhesive, Smith \& Nephew)

the control group C

Group C were covered with paraffin gauze

covered with paraffin gauze

Intervention Type PROCEDURE

Group C covered with paraffin gauze

Interventions

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regrafted with thin split-thickness skin graft

Group A (the treatment group) were regrafted with thin split-thickness skin graft

Intervention Type PROCEDURE

covered with the occlusive hydrocellular dressing

group B covered with the occlusive hydrocellular dressing (Allevyn Adhesive, Smith \& Nephew)

Intervention Type PROCEDURE

covered with paraffin gauze

Group C covered with paraffin gauze

Intervention Type PROCEDURE

Eligibility Criteria

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Inclusion Criteria

* patients who continuously received an STSG from January 2002 to December 2010 in Department of Burn and Plastic Surgery, Tangdu Hospital, Fourth Military Medical University

Exclusion Criteria

* The patients who were significant psychiatric, hypersensitive to silver, and not be followed up were excluded
Minimum Eligible Age

5 Years

Maximum Eligible Age

56 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Tang-Du Hospital

OTHER

Sponsor Role lead

Responsible Party

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Yongqian Bian

Mr Yongqian Bian

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Yongqian Bian, doctor

Role: STUDY_DIRECTOR

specify Unaffiliated

Other Identifiers

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TDLL-2030130

Identifier Type: -

Identifier Source: org_study_id