Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
PHASE4
76 participants
INTERVENTIONAL
2006-08-31
2007-03-31
Brief Summary
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Detailed Description
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Specific Aim: To compare the efficacy of metoclopramide versus prochlorperazine for the emergency department treatment of migraine headaches. Both of these medications will be combined with diphenhydramine to prevent extra-pyramidal side effects.
Patients will be enrolled as participants if they present to one of the participating EDs and consent to participate. Medications will be administered as an intravenous drip over 15 minutes. Rescue medication will be administered, if needed, after one hour. A follow-up phone call will be conducted 24 hours after the ED visit.
Conditions
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Study Design
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RANDOMIZED
PARALLEL
TREATMENT
DOUBLE
Interventions
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Prochlorperazine
Metoclopramide
Eligibility Criteria
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Inclusion Criteria
Exclusion Criteria
* if the patient is to receive a lumbar puncture in the ED
* maximum temperature greater than 100.3 degrees
* new objective neurologic abnormality at the time of physical exam
* allergy or intolerance to a study medication
* pregnancy
* previous enrollment
18 Years
ALL
No
Sponsors
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Albert Einstein College of Medicine
OTHER
Montefiore Medical Center
OTHER
Responsible Party
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Benjamin W. Friedman, MD
Prof. Emergency Medicine
Principal Investigators
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Benjamin W Friedman, MD, MS
Role: PRINCIPAL_INVESTIGATOR
Albert Einstein College of Medicine
Locations
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Montefiore Medical Center
The Bronx, New York, United States
Countries
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Other Identifiers
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06-06-311
Identifier Type: -
Identifier Source: org_study_id
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