Twins and the Risk of Parkinson's Disease: A Clinical and Imaging Study
NCT ID: NCT00282802
Last Updated: 2009-07-02
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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UNKNOWN
250 participants
OBSERVATIONAL
2001-04-30
2010-07-31
Brief Summary
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Detailed Description
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The purpose of the "Twins and the Risk of PD" study is to follow-up previous studies and confirm the initial findings. In this study, investigators will use the NAS/NRC WWII Veteran Twin Cohort Registry to compare the concordance rates for PD in monozygotic and dizygotic twins-at least one of whom has PD.
The overall goal of this research is determine the contributions of genetic and environmental factors in the cause of PD.
The study will involve traditional clinical research methods, such as a clinical examination, as well as innovative imaging techniques, such as single photon emission computed tomography (SPECT). SPECT-a nuclear imaging test involving blood flow to tissue-is used to evaluate certain brain functions.
Findings from this study may help to set research priorities in PD, and to develop tools for early detection of the disorder.
Conditions
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Study Design
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COHORT
PROSPECTIVE
Study Groups
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1
National Academy of Sciences/National Resource Council (NAS/NRC) World War II Veteran Twins Cohort
No interventions assigned to this group
Eligibility Criteria
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Inclusion Criteria
77 Years
88 Years
MALE
No
Sponsors
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National Institute of Neurological Disorders and Stroke (NINDS)
NIH
The Parkinson's Institute
OTHER
Responsible Party
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The Parkinson's Institute
Principal Investigators
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Caroline M. Tanner, MD
Role: PRINCIPAL_INVESTIGATOR
The Parkinson's Institute
Locations
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The Parkinson's Institute, 675 Almanor Avene
Sunnyvale, California, United States
Countries
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Other Identifiers
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