Muscle Relaxation Therapy With Odorant Cue

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

15 participants

Study Classification

INTERVENTIONAL

Study Start Date

2003-11-30

Study Completion Date

2005-05-31

Brief Summary

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A novel procedure for generalized anxiety disorder where an odorant cue is paired with the state of deep relaxation during training. It is hypothesized that by smelling the odor in an anxiety-provoking situation, the patient will more easily invoke a state of relaxation, providing greater relief from the distressing tension and worry that characterize GAD.

Detailed Description

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We hypothesize that by presenting a novel odor to a patient in a state of deep relaxation, the odor will serve as a conditioned inhibitory stimulus, or safety signal, in anxiety-provoking situations. With the odor serving as a contextual cue for the state of relaxation.

Conditions

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Generalized Anxiety Disorder Anxiety

Keywords

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Anxiety Mental Health

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

SINGLE_GROUP

Primary Study Purpose

TREATMENT

Blinding Strategy

SINGLE

Interventions

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Odorant Cue

Intervention Type BEHAVIORAL

Eligibility Criteria

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Inclusion Criteria

* GAD without a comorbid active major psychiatric disorder.
* GAD must be the primary active psychiatric disorder.
* GAD determined via the Mini International Neuropsychiatric Interview (MINI).

Exclusion Criteria

* Significant medical illness that might interfere with the relaxation therapy or with training using the odorant.
* Actively abusing alcohol.
* Illicit substances.
* Currently using rapid-acting anxiolytic agents (e.g. benzodiazepines, hydroxyzine).
* Started an antidepressant, antipsychotic or mood stabilizing agent within three months of screening visit.

Minimum Eligible Age

18 Years

Maximum Eligible Age

65 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Principal Investigators

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Philip T Ninan, MD

Role: PRINCIPAL_INVESTIGATOR

Emory University

Locations

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Emory University School of Medicine

Atlanta, Georgia, United States

Site Status

Countries

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United States

Other Identifiers

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0860-2003

Identifier Type: -

Identifier Source: org_study_id