Light Therapy for Obsessive-compulsive Disorder (OCD)

NCT ID: NCT06720090

Last Updated: 2025-07-15

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Clinical Phase

EARLY_PHASE1

Total Enrollment

40 participants

Study Classification

INTERVENTIONAL

Study Start Date

2024-12-16

Study Completion Date

2029-03-31

Brief Summary

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The goal of this clinical trial is to test whether light therapy is effective for reducing symptoms in young adults with OCD and late bedtimes (1am or later). The main question\[s\] it aims to answer are:

Does light therapy reduce OCD symptoms? Does light therapy advance the circadian clock? If there is a comparison group: Researchers will compare a higher dose of light therapy to a lower dose to see if dose amount affects symptom reduction.

Participants will asked to:

1. Wear light therapy glasses for 1 hour each morning and complete a daily light therapy log for 5 weeks
2. Track their sleep every day with a wearable monitor and an electronic sleep diary for 5 weeks
3. Complete a 1-time assessment of sensitivity to light exposure
4. Complete self-report measures of OCD 4 times/day at baseline (2 weeks), mid-treatment (1 week), and end of treatment (1 week)

Detailed Description

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Conditions

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OCD

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

DOUBLE

Participants Outcome Assessors

Study Groups

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Higher dose

Participants will be given wearable light therapy devices that emit a higher light intensity.

Group Type EXPERIMENTAL

Light therapy

Intervention Type BEHAVIORAL

5 weeks of light therapy administered via wearable light therapy glasses worn for 1 hour each morning after awakening.

Lower dose

Participants will be given wearable light therapy devices that emit a lower light intensity.

Group Type SHAM_COMPARATOR

Light therapy

Intervention Type BEHAVIORAL

5 weeks of light therapy administered via wearable light therapy glasses worn for 1 hour each morning after awakening.

Interventions

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Light therapy

5 weeks of light therapy administered via wearable light therapy glasses worn for 1 hour each morning after awakening.

Intervention Type BEHAVIORAL

Eligibility Criteria

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Inclusion Criteria

1. Primary DSM-5 OCD diagnosis
2. Bedtime 0100 or later
3. Age 18-35
4. English speaking

Exclusion Criteria

1. Subjects must not be currently participating in another research study that would influence their participation in our study.
2. Diagnostic status
3. Treatment status
4. Night shift work or travel more than 1 time zone outside of Central Standard Time (CST) in the past month
5. Pregnancy status
6. Medication status
7. Regular nicotine or marijuana use
Minimum Eligible Age

17 Years

Maximum Eligible Age

35 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Washington University School of Medicine

OTHER

Sponsor Role lead

Responsible Party

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Rebecca C. Cox

Assistant Professor

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Rebecca Cox, PhD

Role: PRINCIPAL_INVESTIGATOR

Washington University School of Medicine

Locations

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Washington University

St Louis, Missouri, United States

Site Status RECRUITING

Countries

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United States

Central Contacts

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Rebecca Cox, BA

Role: CONTACT

314-935-8111

Facility Contacts

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Rebecca Cox, PhD

Role: primary

314-935-8111

Other Identifiers

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K23MH137376

Identifier Type: NIH

Identifier Source: org_study_id

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