Circadian Sleep-wake Cycles and Light Therapy in Borderline Personality Disorder

NCT ID: NCT01311193

Last Updated: 2011-03-09

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Study Classification

INTERVENTIONAL

Brief Summary

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Individuals with borderline personality disorder (BPD) frequently suffer from emotional instability, daytime fatigue and sleep disturbances. The investigators examined circadian rhythms, sleep and well-being in women with BPD under their habitual life conditions with and without light treatment.

Treated women diagnosed with BPD were investigated during 3 weeks without and 3 weeks with morning LT. Rest-activity cycles were continuously measured using wrist actigraphy, together with proximal skin temperature. Saliva samples were collected weekly to determine the diurnal melatonin rhythm. A range of self-ratings and questionnaires were used to assess depression and clinical state throughout the 6-week protocol. Ten matched healthy women followed the same 6-week protocol without light treatment.

Detailed Description

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Conditions

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Borderline Personality Disorder Sleep Disturbances Depression

Study Groups

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light therapy

Morning bright light treatment (at 8000 lux for 40min, daily during 3 weeks)

Group Type EXPERIMENTAL

light therapy

Intervention Type OTHER

early morning exposures to bright light, 8000lux for 40min, daily during 3 weeks

Interventions

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light therapy

early morning exposures to bright light, 8000lux for 40min, daily during 3 weeks

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Borderline Personality Disorder (DSM IV-criteria)
* German-speaking
* normal ocular function

Exclusion Criteria

* lack of compliance
Minimum Eligible Age

20 Years

Maximum Eligible Age

45 Years

Eligible Sex

FEMALE

Accepts Healthy Volunteers

No

Sponsors

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Velux Fonden

OTHER

Sponsor Role collaborator

Lumie UK

UNKNOWN

Sponsor Role collaborator

University Hospital, Basel, Switzerland

OTHER

Sponsor Role lead

Principal Investigators

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Christian Cajochen, PhD

Role: PRINCIPAL_INVESTIGATOR

Centre for Chronobiology, Psychiatric Hospital, University of Basel

Locations

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Centre for Chronobiology, Psychiatric Hospital, University of Basel

Basel, Canton of Basel-City, Switzerland

Site Status

Countries

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Switzerland

Related Links

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Other Identifiers

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Velux-425

Identifier Type: -

Identifier Source: org_study_id

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