Breast Feeding Analgesia in Preterm Infants

NCT ID: NCT00175409

Last Updated: 2011-04-12

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

PHASE1

Total Enrollment

50 participants

Study Classification

INTERVENTIONAL

Study Start Date

2008-01-31

Study Completion Date

2010-06-30

Brief Summary

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The purpose of this study is to compare the effects of mothers' breastfeeding with the effects of pacifier sucking on preterm infant biobehavioural responses during and immediately after a painful procedure

Hypothesis:

1. When breast fed by their mothers during blood collection, preterm infants will show less pain reaction than when sucking on a pacifier.
2. Following breast feeding during the blood collection, mothers will find no differences in their infants' breast feeding ability.

Detailed Description

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Research Method:

In a within subjects, randomized, cross-over design, 50 stable preterm infants born between 30-36 weeks gestational age will be studied. Infants will be randomized to two interventions which will take place during two separate blood collections that are required for clinical management. For the standard care condition, infants will remain in their isolettes and will be positioned in prone and given a pacifier to suck on throughout the blood collection. For the feeding condition, infants will be held and then breast fed by their mother during the blood collection.

Conditions

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Pain

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

PREVENTION

Blinding Strategy

NONE

Study Groups

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1

Infants will be randomized to two interventions which will take place during two separate blood collections that are required for clinical management. For the standard care condition, infants will remain in their isolettes and will be positioned in prone and given a pacifier to suck on throughout the blood collection.

Group Type ACTIVE_COMPARATOR

Blood collection

Intervention Type PROCEDURE

For the standard care condition, infants will remain in their isolettes and will be positioned in prone and given a pacifier to suck on throughout the blood collection.

2

Infants will be randomized to two interventions which will take place during two separate blood collections that are required for clinical management. For the feeding condition, infants will be held and then breast fed by their mother during the blood collection.

Group Type ACTIVE_COMPARATOR

Blood collection

Intervention Type PROCEDURE

For the feeding condition, infants will be held and then breast fed by their mother during the blood collection.

Interventions

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Blood collection

For the standard care condition, infants will remain in their isolettes and will be positioned in prone and given a pacifier to suck on throughout the blood collection.

Intervention Type PROCEDURE

Blood collection

For the feeding condition, infants will be held and then breast fed by their mother during the blood collection.

Intervention Type PROCEDURE

Eligibility Criteria

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Inclusion Criteria

* born between 30-36 weeks gestational age
* breastfeeding
* mother has fluent English

Exclusion Criteria

* CNS injury
* congenital anomaly
* active infection
* has had surgeries or analgesics/sedatives in last 72 hours
* history of maternal drug exposure
Minimum Eligible Age

3 Days

Maximum Eligible Age

37 Weeks

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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SickKids Foundation

OTHER

Sponsor Role collaborator

University of British Columbia

OTHER

Sponsor Role lead

Responsible Party

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University of British Columbia

Principal Investigators

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Liisa Holsti, PhD, OT

Role: PRINCIPAL_INVESTIGATOR

University of British Columbia

Locations

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Lions Gate Hospital - Special Care Nursery

North Vancouver, British Columbia, Canada

Site Status

Children's and Women's Health Centre of British Columbia - Neonatal Intensive Care Unit & Intermediate Care Nursery

Vancouver, British Columbia, Canada

Site Status

Countries

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Canada

Other Identifiers

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C05-0248

Identifier Type: -

Identifier Source: org_study_id

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