Non-pharmacological Analgesic Effects on Term Newborns

NCT ID: NCT03421158

Last Updated: 2018-02-05

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

236 participants

Study Classification

INTERVENTIONAL

Study Start Date

2014-11-07

Study Completion Date

2017-08-31

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

The purpose of this study is to compare the analgesic effects of four non-pharmacological interventions: skin-to-skin contact, breastfeeding, oral sucrose and nonnutritive sucking in newborns receiving a heel lance procedure.

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

This is an randomized control clinical study. study population is healthy term newborns.Patients were identified by chart review and consent was received by nurse researcher. Newborns were randomized into either the control group who received no pain intervention or the intervention group who received one of four non-pharmacological pain interventions: skin to skin contact, breastfeeding, oral sucrose, and nonnutritive sucking.

A heel lance for newborn screen blood sampling was selected as a study procedure and performed by a hospital technician following standard protocol. Pain scoring was assessed by two research nurses after the hell lance and through the procedure. Neonatal Pain, Agitation and Sedation Scale (NPASS) was selected as a pain assessment tool for this study.

The average pain score from two research nurses were used for statistical analysis.

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Pain Breast Feeding

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

Review each arm or cohort in the study, along with the interventions and objectives associated with them.

Control

Newborns received no pain interventions during the procedure

Group Type NO_INTERVENTION

No interventions assigned to this group

Breastfeeding

Newborns were breastfed during the procedure

Group Type EXPERIMENTAL

breastfeeding

Intervention Type BEHAVIORAL

Newborns were breastfed during the procedure

Oral Sucrose

Newborns were given oral sucrose during the procedure

Group Type EXPERIMENTAL

oral sucrose

Intervention Type DIETARY_SUPPLEMENT

Newborns were given oral sucrose during the procedure

Skin to skin contact

Newborns were placed in direct contact with their mothers during the procedure

Group Type EXPERIMENTAL

Skin-to-Skin contact

Intervention Type BEHAVIORAL

Newborns were placed in direct contact with their mothers during the procedure

Non-nutritive sucking

Newborns were given a pacifier to suck on during the procedure

Group Type EXPERIMENTAL

Non-nutritive sucking

Intervention Type BEHAVIORAL

newborns were given a pacifier to suck on during the procedure

Interventions

Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.

breastfeeding

Newborns were breastfed during the procedure

Intervention Type BEHAVIORAL

oral sucrose

Newborns were given oral sucrose during the procedure

Intervention Type DIETARY_SUPPLEMENT

Skin-to-Skin contact

Newborns were placed in direct contact with their mothers during the procedure

Intervention Type BEHAVIORAL

Non-nutritive sucking

newborns were given a pacifier to suck on during the procedure

Intervention Type BEHAVIORAL

Other Intervention Names

Discover alternative or legacy names that may be used to describe the listed interventions across different sources.

Pacifier

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

* Gestational Age 38-40
* 2.5-4.0kg
* 24-48hours of age
* Receiving heel lance procedure
* Apgar\>7 at birth
* NPASS\<3 at time of heel lance

Exclusion Criteria

* Prior heel lance procedure
* birth trauma
* forceps or vacuum delivery
* maternal drug abuse during delivery
Minimum Eligible Age

24 Hours

Maximum Eligible Age

48 Hours

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

Meet the organizations funding or collaborating on the study and learn about their roles.

Stanford University

OTHER

Sponsor Role lead

Responsible Party

Identify the individual or organization who holds primary responsibility for the study information submitted to regulators.

Annette Nasr

Clinical Assistant Professor, Pediatrics

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

Learn about the lead researchers overseeing the trial and their institutional affiliations.

Jie Chang, BSN,MD

Role: PRINCIPAL_INVESTIGATOR

Stanford University

Other Identifiers

Review additional registry numbers or institutional identifiers associated with this trial.

31216

Identifier Type: -

Identifier Source: org_study_id

More Related Trials

Additional clinical trials that may be relevant based on similarity analysis.

Nonpharmacological Pain Management in Neonates
NCT06155825 NOT_YET_RECRUITING NA