Losartan and HCTZ and Amlodipine vs Atenolol and Amlodipine (0954A-309)(COMPLETED)

NCT ID: NCT00140959

Last Updated: 2024-08-15

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

PHASE4

Total Enrollment

120 participants

Study Classification

INTERVENTIONAL

Study Start Date

2003-02-01

Study Completion Date

2004-06-30

Brief Summary

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A study to evaluate the effects of combination losartan versus combination atenolol in patients with ambulatory systolic hypertension.

Detailed Description

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Conditions

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Hypertension

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Interventions

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MK0954, losartan potassium/Duration of Treatment: 18 weeks

Intervention Type DRUG

Comparator: losartan, HCTZ, amlodipine, atenolol/Duration of Treatment: 18 weeks

Intervention Type DRUG

Eligibility Criteria

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Inclusion Criteria

* Males or females at least 18 years of age who have ambulatory systolic hypertension.
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Organon and Co

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Medical Monitor

Role: STUDY_DIRECTOR

Merck Sharp & Dohme LLC

References

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Lacourciere Y, Poirier L, Lefebvre J. Expedited blood pressure control with initial angiotensin II antagonist/diuretic therapy compared with stepped-care therapy in patients with ambulatory systolic hypertension. Can J Cardiol. 2007 Apr;23(5):377-82. doi: 10.1016/s0828-282x(07)70771-7.

Reference Type BACKGROUND
PMID: 17440643 (View on PubMed)

Other Identifiers

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2005_061

Identifier Type: -

Identifier Source: secondary_id

0954A-309

Identifier Type: -

Identifier Source: org_study_id

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