Compassionate Use of Stanate (TM) [Stannsoporfin]

NCT ID: NCT00076960

Last Updated: 2019-10-15

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

NO_LONGER_AVAILABLE

Study Classification

EXPANDED_ACCESS

Brief Summary

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The purpose of this protocol is to make Stanate (TM) \[stannsoporfin, tin-mesoporphyrin\] available to infants who meet the following criteria:

1. the infant has a very high level of bilirubin without an adequate clinical response to phototherapy;
2. the infant requires an exchange transfusion; and
3. the family refuses to allow the administration of blood products, particularly on religious grounds, such as within the Jehovah's Witness community.

Detailed Description

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Conditions

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Neonatal Jaundice Hyperbilirubinemia

Interventions

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Stanate (TM) [stannsoporfin, tin-mesoporphyrin]

Treatment with 4.5 mg/kg

Intervention Type DRUG

Eligibility Criteria

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Inclusion Criteria

* Term or near term neonate
* Elevated serum bilirubin
* Failing phototherapy
* Requires exchange transfusion
* Family refuses exchange transfusion on religious grounds
Minimum Eligible Age

12 Hours

Maximum Eligible Age

1 Week

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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InfaCare Pharmaceuticals Corporation, a Mallinckrodt Company

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Locations

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William Beaumont Hospital

Royal Oak, Michigan, United States

Site Status

Countries

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United States

References

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Kappas A, Drummond GS, Munson DP, Marshall JR. Sn-Mesoporphyrin interdiction of severe hyperbilirubinemia in Jehovah's Witness newborns as an alternative to exchange transfusion. Pediatrics. 2001 Dec;108(6):1374-7. doi: 10.1542/peds.108.6.1374.

Reference Type BACKGROUND
PMID: 11731664 (View on PubMed)

Other Identifiers

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99A

Identifier Type: -

Identifier Source: org_study_id

NCT01183988

Identifier Type: -

Identifier Source: nct_alias

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