A Phase III Study of Entecavir vs Lamivudine in Adults With Chronic Hepatitis B Infection and Negative for Hepatitis B e Antigen
NCT ID: NCT00035789
Last Updated: 2011-04-14
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
PHASE3
INTERVENTIONAL
2001-11-30
2005-05-31
Brief Summary
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Detailed Description
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Conditions
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Study Design
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TREATMENT
Interventions
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Entecavir
Eligibility Criteria
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Inclusion Criteria
* HBeAg negative, anti-HBeAb positive;
* Absence of coinfection with human immunodeficiency virus (HIV), hepatitis C virus (HCV) or hepatitis D virus (HDV);
* Absence of other forms of liver disease e.g., alcoholic, autoimmune, biliary disease;
* Less than 12 weeks prior therapy with nucleoside or nucleotide analogue antiviral agents with activity against hepatitis B (e.g., adefovir, famciclovir and lamivudine)
16 Years
ALL
No
Sponsors
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Bristol-Myers Squibb
INDUSTRY
Locations
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Local Investigator
Birmingham, Alabama, United States
Local Investigator
Tucson, Arizona, United States
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La Jolla, California, United States
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Los Angeles, California, United States
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Orange, California, United States
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San Francisco, California, United States
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Farmington, Connecticut, United States
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Miami Beach, Florida, United States
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Atlanta, Georgia, United States
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Honolulu, Hawaii, United States
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Chicago, Illinois, United States
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Iowa City, Iowa, United States
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Kansas City, Kansas, United States
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Dundalk, Maryland, United States
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Worcester, Massachusetts, United States
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Ann Arbor, Michigan, United States
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Royal Oak, Michigan, United States
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Saint Paul, Minnesota, United States
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Manhasset, New York, United States
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New York, New York, United States
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Rochester, New York, United States
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Charlotte, North Carolina, United States
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Cleveland, Ohio, United States
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Philadelphia, Pennsylvania, United States
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Pittsburgh, Pennsylvania, United States
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Providence, Rhode Island, United States
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Nashville, Tennessee, United States
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Dallas, Texas, United States
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Fairfax, Virginia, United States
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Richmond, Virginia, United States
Local Investigator
Seattle, Washington, United States
Countries
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References
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Lai CL, Shouval D, Lok AS, Chang TT, Cheinquer H, Goodman Z, DeHertogh D, Wilber R, Zink RC, Cross A, Colonno R, Fernandes L; BEHoLD AI463027 Study Group. Entecavir versus lamivudine for patients with HBeAg-negative chronic hepatitis B. N Engl J Med. 2006 Mar 9;354(10):1011-20. doi: 10.1056/NEJMoa051287.
Other Identifiers
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AI463-027
Identifier Type: -
Identifier Source: org_study_id
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